Birgitta Stegmayr1, Marie Eriksson, Kjell Asplund. 1. Department Public Health and Clinical Medicine, Umeå University Hospital, SE-901 85 Umeå, Sweden. birgitta.stegmayr@medicin.umu.se
Abstract
BACKGROUND AND PURPOSE: Northern Sweden has one of the highest incidence rates of subarachnoid hemorrhage (SAH) among the populations covered by the WHO MONICA (Monitoring of Trends and Determinants in Cardiovascular Disease) Project, approximately twice as high as in the other populations in Europe. In this study, trends in incidence, 28-day case fatality (CF), and mortality in SAH were followed over a 16-year period. METHODS: Since 1985, all SAHs in northern Sweden among patients 25 to 74 years old have been validated using strict MONICA criteria. From 1985 through 2000, 392 men and 592 women had SAH. During 3 years, 1997 to 1999, SAH among those aged 75 and older were also included. RESULTS: The total incidence among those 25 years and older was 13.3 per 100 000 in men and 24.4 per 100 000 in women. During the 16 years of observation, age standardized incidence in the group aged 25 to 74 years decreased significantly in men (P for trend <0.0001) but remained essentially unchanged in women (P for trend=0.64). The 28-day CF for all years was 36.5% in men, with no significant trend (P=0.7). In women, average CF was 35%, with a significant decline (P=0.003). The annual mortality decreased significantly in both sexes (by 3.87 [95% CI+/-2.75 percentage points] in men and 3.97 [95% CI+/-2.29] in women). CONCLUSIONS: The decline in SAH mortality has different explanations in men (declining incidence) and in women (declining CF).
BACKGROUND AND PURPOSE: Northern Sweden has one of the highest incidence rates of subarachnoid hemorrhage (SAH) among the populations covered by the WHO MONICA (Monitoring of Trends and Determinants in Cardiovascular Disease) Project, approximately twice as high as in the other populations in Europe. In this study, trends in incidence, 28-day case fatality (CF), and mortality in SAH were followed over a 16-year period. METHODS: Since 1985, all SAHs in northern Sweden among patients 25 to 74 years old have been validated using strict MONICA criteria. From 1985 through 2000, 392 men and 592 women had SAH. During 3 years, 1997 to 1999, SAH among those aged 75 and older were also included. RESULTS: The total incidence among those 25 years and older was 13.3 per 100 000 in men and 24.4 per 100 000 in women. During the 16 years of observation, age standardized incidence in the group aged 25 to 74 years decreased significantly in men (P for trend <0.0001) but remained essentially unchanged in women (P for trend=0.64). The 28-day CF for all years was 36.5% in men, with no significant trend (P=0.7). In women, average CF was 35%, with a significant decline (P=0.003). The annual mortality decreased significantly in both sexes (by 3.87 [95% CI+/-2.75 percentage points] in men and 3.97 [95% CI+/-2.29] in women). CONCLUSIONS: The decline in SAH mortality has different explanations in men (declining incidence) and in women (declining CF).
Authors: Jasper H van Lieshout; Maxine Dibué-Adjei; Jan F Cornelius; Philipp J Slotty; Toni Schneider; Tanja Restin; Hieronymus D Boogaarts; Hans-Jakob Steiger; Athanasios K Petridis; Marcel A Kamp Journal: Neurosurg Rev Date: 2017-02-18 Impact factor: 3.042
Authors: Marcel A Kamp; Jasper H van Lieshout; Maxine Dibué-Adjei; Jasmin K Weber; Toni Schneider; Tanja Restin; Igor Fischer; Hans-Jakob Steiger Journal: Transl Stroke Res Date: 2017-01-30 Impact factor: 6.829
Authors: Athanasios K Petridis; Marcel A Kamp; Jan F Cornelius; Thomas Beez; Kerim Beseoglu; Bernd Turowski; Hans-Jakob Steiger Journal: Dtsch Arztebl Int Date: 2017-03-31 Impact factor: 5.594
Authors: N K de Rooij; F H H Linn; J A van der Plas; A Algra; G J E Rinkel Journal: J Neurol Neurosurg Psychiatry Date: 2007-04-30 Impact factor: 10.154
Authors: Nefize Turan; Robert Allen-James Heider; Dobromira Zaharieva; Faiz U Ahmad; Daniel L Barrow; Gustavo Pradilla Journal: Transl Stroke Res Date: 2015-11-16 Impact factor: 6.829