| Literature DB >> 15272071 |
Yukio Morita1, Soichi Maruyama1, Hidenori Kabeya1, Akira Nagai1, Kunihisa Kozawa1, Masahiko Kato1, Takashi Nakajima1, Takeshi Mikami1, Yasuji Katsube1, Hirokazu Kimura1.
Abstract
The Mycobacterium avium complex (MAC) is associated with various diseases in humans as a zoonosis. The dnaJ gene was partially sequenced in Schaefer's 28 reference strains of MAC, 14 human MAC isolates and 22 veterinary isolates. From substitutions affecting 21-32 nucleotides, all strains could be classified into 14 groups. Most nucleotide substitutions did not alter amino acid sequences. Approximately 8 % genetic diversity was seen in these strains, which divided into two clusters: cluster I (0.8 % genetic diversity), comprising the reference strain serotypes 1-6, 8-11 and 21 and all isolates; and cluster II (7 % genetic diversity), comprising the remaining reference strains. Analysis of the dnaJ gene in MAC may be useful in epidemiological studies. Copyright 2004 SGMEntities:
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Year: 2004 PMID： 15272071 DOI： 10.1099/jmm.0.45601-0
Source DB: PubMed Journal: J Med Microbiol ISSN： 0022-2615 Impact factor: 2.472