| Literature DB >> 15271472 |
J L Juengel1, K J Bodensteiner, D A Heath, N L Hudson, C L Moeller, P Smith, S M Galloway, G H Davis, H R Sawyer, K P McNatty.
Abstract
Two related oocyte-derived members of the transforming growth factor-beta (TGF-beta) superfamily, namely growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, also known as GDF9B), have recently been shown to be essential for ovarian follicular growth. In addition, both proteins have been shown to regulate ovulation rate in sheep, and although it is evident that these growth factors interact both with one another and with other intra- and extra-ovarian factors, the precise mechanisms by which they influence follicular growth and ovulation rate have not been thoroughly elucidated.Entities:
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Year: 2004 PMID： 15271472 DOI： 10.1016/j.anireprosci.2004.04.021
Source DB: PubMed Journal: Anim Reprod Sci ISSN： 0378-4320 Impact factor: 2.145