Literature DB >> 15271343

Daptomycin structure and mechanism of action revealed.

Jason Micklefield1.   

Abstract

Daptomycin kills otherwise antibiotic-resistant gram-positive pathogens and is the first lipopeptide antibiotic to reach the clinic. Elucidation of its 3D structure and mechanism of action, reported in this issue of Chemistry & Biology, will facilitate the design and engineering of new, potentially life-saving antibiotics.

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Year:  2004        PMID: 15271343     DOI: 10.1016/j.chembiol.2004.07.001

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  7 in total

1.  Antimicrobial activities of daptomycin, vancomycin, and oxacillin in human monocytes and of daptomycin in combination with gentamicin and/or rifampin in human monocytes and in broth against Staphylococcus aureus.

Authors:  Aldona L Baltch; William J Ritz; Lawrence H Bopp; Phyllis B Michelsen; Raymond P Smith
Journal:  Antimicrob Agents Chemother       Date:  2007-02-05       Impact factor: 5.191

2.  Impact of PrsA on membrane lipid composition during daptomycin-resistance-mediated β-lactam sensitization in clinical MRSA strains.

Authors:  Carla C C R de Carvalho; Agustina Taglialegna; Adriana E Rosato
Journal:  J Antimicrob Chemother       Date:  2021-12-24       Impact factor: 5.758

Review 3.  Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides.

Authors:  Jan Grünewald; Mohamed A Marahiel
Journal:  Microbiol Mol Biol Rev       Date:  2006-03       Impact factor: 11.056

4.  Ketamine inhibits tumor necrosis factor secretion by RAW264.7 murine macrophages stimulated with antibiotic-exposed strains of community-associated, methicillin-resistant Staphylococcus aureus.

Authors:  Thomas Spentzas; Rebekah K H Shapley; Carlos Acuna Aguirre; Elizabeth Meals; Lauren Lazar; Mark S Rayburn; Brett S Walker; B Keith English
Journal:  BMC Immunol       Date:  2011-01-25       Impact factor: 3.615

Review 5.  Daptomycin: a cyclic lipopeptide antimicrobial agent.

Authors:  LilyAnn Jeu; Horatio B Fung
Journal:  Clin Ther       Date:  2004-11       Impact factor: 3.393

Review 6.  Multidrug Resistance (MDR) and Collateral Sensitivity in Bacteria, with Special Attention to Genetic and Evolutionary Aspects and to the Perspectives of Antimicrobial Peptides-A Review.

Authors:  András Fodor; Birhan Addisie Abate; Péter Deák; László Fodor; Ervin Gyenge; Michael G Klein; Zsuzsanna Koncz; Josephat Muvevi; László Ötvös; Gyöngyi Székely; Dávid Vozik; László Makrai
Journal:  Pathogens       Date:  2020-06-29

Review 7.  Impact on Antibiotic Resistance, Therapeutic Success, and Control of Side Effects in Therapeutic Drug Monitoring (TDM) of Daptomycin: A Scoping Review.

Authors:  Carolina Osorio; Laura Garzón; Diego Jaimes; Edwin Silva; Rosa-Helena Bustos
Journal:  Antibiotics (Basel)       Date:  2021-03-05
  7 in total

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