Literature DB >> 15270580

New cytotoxic cembranes from the sea pen Gyrophyllum sibogae.

Fernando Reyes1, Ana Ardá, Rocío Martín, Rogelio Fernández, Ana Rueda, David Montalvo, Cristina Gómez, Carlos Jiménez, Jaime Rodríguez, José Maria Sánchez-Puelles.   

Abstract

Two new cembrane-type diterpenoids have been isolated from the 2-propanol extract of the sea pen Gyrophyllum sibogae collected in South Africa: 7,8-dihydroflabellatene A (1) and 7,8-dihydroflabellatene B (2). Their structures were determined on the basis of detailed spectroscopic analysis and by single-crystal X-ray analysis of the major metabolite 1, which showed strong in vitro cytotoxicity against a panel of 13 tumor cell lines.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15270580     DOI： 10.1021/np049903m

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia cell lines.

Authors:  Andrea A Stierle; Donald B Stierle; Teri Girtsman
Journal:  J Nat Prod       Date:  2012-02-01       Impact factor: 4.050

2.  Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate.

Authors:  P Li; D E Reichert; A D Rodríguez; B D Manion; A S Evers; V A Eterović; J H Steinbach; G Akk
Journal:  Br J Pharmacol       Date:  2007-11-26       Impact factor: 8.739

3.  Inducing Apoptosis of Cancer Cells Using Sea Pen Virgularia gustaviana Extract Which is Comparable to Cembrane Diterpene Sarcophine.

Authors:  Sharareh Sharifi; Pargol Ghavam Mostafavi; Ali Mashinchian Moradi; Mohammad Hadi Givianrad; Hassan Niknejad
Journal:  Iran J Pharm Res       Date:  2018       Impact factor: 1.696

4.  Cytotoxic Anomoian B and Aplyzanzine B, New Bromotyrosine Alkaloids from Indonesian Sponges.

Authors:  Guillermo Tarazona; Gema Santamaría; Patricia G Cruz; Rogelio Fernández; Marta Pérez; Juan Fernando Martínez-Leal; Jaime Rodríguez; Carlos Jiménez; Carmen Cuevas
Journal:  ACS Omega       Date:  2017-07-12

5.  Absolute configuration by vibrational circular dichroism of anti-inflammatory macrolide briarane diterpenoids from the Gorgonian Briareum asbestinum.

Authors:  Dawrin Pech-Puch; Pedro Joseph-Nathan; Eleuterio Burgueño-Tapia; Carlos González-Salas; Diana Martínez-Matamoros; David M Pereira; Renato B Pereira; Carlos Jiménez; Jaime Rodríguez
Journal:  Sci Rep       Date:  2021-01-12       Impact factor: 4.379

Review 6.  Diterpenes from the Marine Algae of the Genus Dictyota.

Authors:  Jiayun Chen; Hong Li; Zishuo Zhao; Xue Xia; Bo Li; Jinrong Zhang; Xiaojun Yan
Journal:  Mar Drugs       Date:  2018-05-11       Impact factor: 5.118
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.