Literature DB >> 15270574

New lamellarin alkaloids from the Indian ascidian Didemnum obscurum and their antioxidant properties.

P Krishnaiah1, V L N Reddy, G Venkataramana, K Ravinder, M Srinivasulu, T V Raju, K Ravikumar, D Chandrasekar, S Ramakrishna, Y Venkateswarlu.   

Abstract

Three new lamellarin alkaloids, lamellarins gamma (1), alpha (2), and epsilon (3), along with eight known lamellarin alkaloids, lamellarins M (4), K (5), K-diacetate (6), K-triacetate (7), U (8), I (9), C-diacetate (10), and X-triacetate (11), have been isolated from the Indian ascidian Didemnum obscurum. The structures of 1-11 were established using standard spectroscopic techniques. The structure of lamellarin K-triacetate (7) was further confirmed by X-ray crystallographic analysis. The antioxidant properties of lamellarin gamma, lamellarin gamma-monoacetate, lamellarins K, U, and I, and lamellarin C-diacetate were evaluated.

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Year:  2004        PMID: 15270574     DOI: 10.1021/np030503t

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  13 in total

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Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2007-02-09       Impact factor: 3.228

Review 2.  High-value compounds from the molluscs of marine and estuarine ecosystems as prospective functional food ingredients: An overview.

Authors:  Kajal Chakraborty; Minju Joy
Journal:  Food Res Int       Date:  2020-08-31       Impact factor: 6.475

3.  3-bromohomofascaplysin A, a fascaplysin analogue from a Fijian Didemnum sp. ascidian.

Authors:  Zhenyu Lu; Yuanqing Ding; Xing-Cong Li; Daignon R Djigbenou; Brian T Grimberg; Daneel Ferreira; Chris M Ireland; Ryan M Van Wagoner
Journal:  Bioorg Med Chem       Date:  2011-06-01       Impact factor: 3.641

Review 4.  Lamellarins and related pyrrole-derived alkaloids from marine organisms.

Authors:  Hui Fan; Jiangnan Peng; Mark T Hamann; Jin-Feng Hu
Journal:  Chem Rev       Date:  2007-12-21       Impact factor: 60.622

5.  [3 + 2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor.

Authors:  Alexander V Aksenov; Nikolai A Arutiunov; Nikita K Kirilov; Dmitrii A Aksenov; Igor Yu Grishin; Nicolai A Aksenov; Huifen Wang; Liqin Du; Tania Betancourt; Stephen C Pelly; Alexander Kornienko; Michael Rubin
Journal:  Org Biomol Chem       Date:  2021-08-13       Impact factor: 3.890

6.  Didemnaketals f and g, new bioactive spiroketals from a red sea ascidian didemnum species.

Authors:  Lamiaa A Shaala; Diaa T A Youssef; Sabrin R M Ibrahim; Gamal A Mohamed; Jihan M Badr; April L Risinger; Susan L Mooberry
Journal:  Mar Drugs       Date:  2014-09-25       Impact factor: 5.118

Review 7.  Anticancer properties of lamellarins.

Authors:  Christian Bailly
Journal:  Mar Drugs       Date:  2015-02-19       Impact factor: 5.118

8.  Modification of marine natural product ningalin B and SAR study lead to potent P-glycoprotein inhibitors.

Authors:  Chao Yang; Iris L K Wong; Wen Bin Jin; Tao Jiang; Larry M C Chow; Sheng Biao Wan
Journal:  Mar Drugs       Date:  2014-10-17       Impact factor: 5.118

Review 9.  Synthetic approaches to the lamellarins--a comprehensive review.

Authors:  Dennis Imbri; Johannes Tauber; Till Opatz
Journal:  Mar Drugs       Date:  2014-12-18       Impact factor: 5.118

10.  Gold-catalyzed formation of pyrrolo- and indolo-oxazin-1-one derivatives: The key structure of some marine natural products.

Authors:  Sultan Taskaya; Nurettin Menges; Metin Balci
Journal:  Beilstein J Org Chem       Date:  2015-05-28       Impact factor: 2.883

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