Literature DB >> 15269192

Development of a prescribing indicator for objective quantification of antibiotic usage in secondary care.

Chris Curtis1, John Marriott, Chris Langley.   

Abstract

OBJECTIVES: To compare the recognized defined daily dose per 100 bed-days (DDD/100 bed-days) measure with the defined daily dose per finished consultant episode (DDD/FCE) in a group of hospitals with a variety of medicines management strategies. To compare antibiotic usage using the above indicators in hospitals with and without electronic prescribing systems.
METHODS: Twelve hospitals were used in the study. Nine hospitals were selected and split into three cohorts (three high-scoring, three medium-scoring and three low-scoring) by their 2001 medicines management self-assessment scores (MMAS). An additional cohort of three electronic prescribing hospitals was included for comparison. MMAS were compared to antibiotic management scores (AMS) developed from a questionnaire relating specifically to control of antibiotics. FCEs and occupied bed-days were obtained from published statistics and statistical analyses of the DDD/100 bed-days and DDD/FCE were carried out using SPSS.
RESULTS: The DDD/100 bed-days varied from 81.33 to 189.37 whilst the DDD/FCE varied from 2.88 to 7.43. The two indicators showed a high degree of correlation with r=0.74. MMAS were from 9 to 22 (possible range 0-23) and the AMS from 2 to 13 (possible range 0-22). The two scores showed a high degree of correlation with r=0.74. No correlation was established between either indicator and either score.
CONCLUSIONS: The WHO indicator for medicines utilization, DDD/100 bed-days, exhibited the same level of conformity as that exhibited from the use of the DDD/FCE indicating that the DDD/FCE is a useful additional indicator for identifying hospitals which require further study. The MMAS can be assumed to be an accurate guide to antibiotic medicines management controls. No relationship has been found between a high degree of medicines management control and the quantity of antibiotic prescribed.

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Year:  2004        PMID: 15269192     DOI: 10.1093/jac/dkh362

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  5 in total

1.  Complicated community-acquired soft tissue infection by MRSA from porcine origin.

Authors:  Ph Declercq; D Petré; B Gordts; A Voss
Journal:  Infection       Date:  2007-10-31       Impact factor: 3.553

2.  Evaluation of a tool to benchmark hospital antibiotic prescribing in the United Kingdom.

Authors:  Raymond W Fitzpatrick; Catherine M C Edwards
Journal:  Pharm World Sci       Date:  2007-08-08

3.  Sources of European drug consumption data at a country level.

Authors:  Pili Ferrer; Elena Ballarín; Mònica Sabaté; Joan-Ramon Laporte; Marieke Schoonen; Marietta Rottenkolber; Joan Fortuny; Joerg Hasford; Iain Tatt; Luisa Ibáñez
Journal:  Int J Public Health       Date:  2014-05-30       Impact factor: 3.380

4.  Hospital- and patient-related factors associated with differences in hospital antibiotic use: analysis of national surveillance results.

Authors:  Jon Birger Haug; Dag Berild; Mette Walberg; Åsmund Reikvam
Journal:  Antimicrob Resist Infect Control       Date:  2014-12-24       Impact factor: 4.887

5.  Antimicrobial Stewardship from Policy to Practice: Experiences from UK Antimicrobial Pharmacists.

Authors:  Mark Gilchrist; Paul Wade; Diane Ashiru-Oredope; Philip Howard; Jacqueline Sneddon; Laura Whitney; Hayley Wickens
Journal:  Infect Dis Ther       Date:  2015-09-11
  5 in total

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