Literature DB >> 15267184

Pilot study of a novel mandibular advancement device for the control of snoring.

Olivier M Vanderveken1, An N Boudewyns, Marc J Braem, Walter Okkerse, Johan A Verbraecken, Marc Willemen, Floris L Wuyts, Wilfried A De Backer, Paul H Van de Heyning.   

Abstract

OBJECTIVE: Mandibular advancement devices (MADs) have been introduced as a conservative, non-invasive treatment for socially disturbing snoring and mild obstructive sleep apnea (OSA). A prospective, non-randomized pilot study was conducted to investigate the efficacy, feasibility, side-effects and compliance of Somnoguard, an immediately intraorally adaptable MAD made from thermoplastic material.
MATERIAL AND METHODS: Twenty consecutive heavy snorers with a respiratory disturbance index of <20 events/h were prospectively selected. Prior to the adaptation of the appliance, ambulatory polygraphy was carried out without a MAD. After a 1-month habituation period, a polygraphic evaluation was carried out with the device. Treatment success was defined as a reduction in the apnea-hypopnea index (AHI) of at least 50%.
RESULTS: The results indicated a success rate of 65%. The AHI decreased from 8.4 +/- 2.9 events/h at baseline to 3.9 +/- 1.8 events/h with the device (p = 0.001). At 1-month follow-up, significant reductions in the snoring index (p < 0.001) and the Epworth Sleepiness Scale (ESS) score (p = 0.036) were noted. At 6-month follow-up, similar results were achieved, with significant drops in the snoring index (p = 0.025) and ESS score (p = 0.033).
CONCLUSION: We conclude that immediate intraoral adaptation of a low-cost fabricated "one-size-only" MAD is a feasible and well-tolerated treatment for snoring and mild OSA. Further research is needed to evaluate this thermoplastic appliance as a strategy to "screen" the efficacy of MAD treatment in the individual patient with a less expensive appliance before constructing a more expensive custom-made MAD.

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Year:  2004        PMID: 15267184     DOI: 10.1080/00016480310015984

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  9 in total

1.  Oral appliances for treatment of snoring and obstructive sleep apnea: a review of clinical effectiveness.

Authors: 
Journal:  CADTH Technol Overv       Date:  2010-03-01

2.  Can gestational hypertension be modified by treating nocturnal airflow limitation?

Authors:  John Reid; Regina Taylor-Gjevre; John Gjevre; Robert Skomro; Mark Fenton; Femi Olatunbosun; John R Gordon; David Cotton
Journal:  J Clin Sleep Med       Date:  2013-04-15       Impact factor: 4.062

3.  Diagnosis and treatment of snoring in adults-S2k Guideline of the German Society of Otorhinolaryngology, Head and Neck Surgery.

Authors:  Boris A Stuck; Alfred Dreher; Clemens Heiser; Michael Herzog; Thomas Kühnel; Joachim T Maurer; Hans Pistner; Helmut Sitter; Armin Steffen; Thomas Verse
Journal:  Sleep Breath       Date:  2014-04-13       Impact factor: 2.816

4.  Impact of type D personality on adherence to oral appliance therapy for sleep-disordered breathing.

Authors:  M Dieltjens; O M Vanderveken; D Van den Bosch; K Wouters; J Denollet; J A Verbraecken; P H Van de Heyning; M J Braem
Journal:  Sleep Breath       Date:  2012-11-13       Impact factor: 2.816

5.  [Sk2 guidelines"diagnosis and therapy of snoring in adults" : compiled by the sleep medicine working group of the German Society of Otorhinolaryngology, Head and Neck Surgery].

Authors:  B A Stuck; A Dreher; C Heiser; M Herzog; T Kühnel; J T Maurer; H Pistner; H Sitter; A Steffen; T Verse
Journal:  HNO       Date:  2013-11       Impact factor: 1.284

Review 6.  Review of oral appliances for treatment of sleep-disordered breathing.

Authors:  Victor Hoffstein
Journal:  Sleep Breath       Date:  2007-03       Impact factor: 2.816

7.  Pilot Study of a New Adjustable Thermoplastic Mandibular Advancement Device for the Management of Obstructive Sleep Apnoea-Hypopnoea Syndrome: A Brief Research Letter.

Authors:  Mohammed El Ibrahimi; Mounir Laabouri
Journal:  Open Respir Med J       Date:  2016-07-15

8.  Treatment of obstructive sleep apnea using a custom-made titratable duobloc oral appliance: a prospective clinical study.

Authors:  M Dieltjens; O M Vanderveken; E Hamans; J A Verbraecken; K Wouters; M Willemen; W A De Backer; P H Van de Heyning; M J Braem
Journal:  Sleep Breath       Date:  2012-05-13       Impact factor: 2.816

9.  Impact of upper airway abnormalities on the success and adherence to mandibular advancement device treatment in patients with Obstructive Sleep Apnea Syndrome.

Authors:  Renato Prescinotto; Fernanda Louise Martinho Haddad; Ilana Fukuchi; Luiz Carlos Gregório; Paulo Afonso Cunali; Sérgio Tufik; Lia Rita Azeredo Bittencourt
Journal:  Braz J Otorhinolaryngol       Date:  2015-09-07
  9 in total

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