Literature DB >> 15264246

Thromboprophylaxis for radical prostatectomy: a comparative analysis of present practice between the USA, the UK, and Ireland.

David J Galvin1, David Mulvin, David M Quinlan.   

Abstract

BACKGROUND: A clinical dilemma exists in the management of patients undergoing radical prostatectomy (RP) whereby measures taken to reduce the risk of thrombotic events may adversely affect efforts to limit blood loss. No consensus exists in the literature on the ideal management of thromboprophylaxis in these patients. Our aim is to examine and compare current thromboprophylactic policy and practice between the centres involved in performing RP.
METHODS: A questionnaire was forwarded to all urology residency programmes in Ireland, the United Kingdom, and the United States, regarding their current practice with respect to thromboprophylaxis in RP. Completed questionnaire were returned by fax and the data entered into a computer database.
RESULTS: An overall response rate of 60% was achieved. The questionnaires demonstrated a significant difference in clinical practice between Urologists in the United States and the United Kingdom. Just 24% of American Urologists use pharmacological thromboprophylaxis in contrast to 100% of British Urologists. There was no difference in the use of non-pharmacological thromboprophylaxis. Pharmacological thromboprophylaxis is mainly administered by units, mostly in the United Kingdom, doing fewer radical prostatectomies.
CONCLUSIONS: While there have been studies advocating the use of pharmacological thromboprophylaxis in patients undergoing major pelvic surgery, there is no consensus on it is use in urological practice. This study has demonstrated significant differences in the management of thromboprophylaxis between the USA and the UK/Ireland. Units performing the largest number of radical prostatectomies, mostly in the USA, do not use pharmacological thromboprophylaxis and most do not use compression boots.

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Year:  2004        PMID: 15264246     DOI: 10.1002/pros.20063

Source DB:  PubMed          Journal:  Prostate        ISSN: 0270-4137            Impact factor:   4.104


  5 in total

1.  Nationwide practice patterns for the use of venous thromboembolism prophylaxis among men undergoing radical prostatectomy.

Authors:  Aaron Weinberg; Jason Wright; Christopher Deibert; Yu-Shiang Lu; Dawn Hershman; Alfred Neugut; Benjamin Spencer
Journal:  World J Urol       Date:  2013-11-29       Impact factor: 4.226

2.  Thromboprophylaxis in radical retropubic prostatectomy: efficacy and patient compliance of a dual modality.

Authors:  Luca Cindolo; Luigi Salzano; Vincenzo Mirone; Ciro Imbimbo; Nicola Longo; Stavros K Kakkos; Daniel J Reddy
Journal:  Urol Int       Date:  2009-07-27       Impact factor: 2.089

3.  Follow-up of thrombin generation after prostate cancer surgery: global test for increased hypercoagulability.

Authors:  Matyas Benyo; Tibor Flasko; Zsuzsanna Molnar; Adrienne Kerenyi; Zoltan Batta; Tamas Jozsa; Jolan Harsfalvi
Journal:  PLoS One       Date:  2012-12-07       Impact factor: 3.240

Review 4.  Systematic reviews of observational studies of risk of thrombosis and bleeding in urological surgery (ROTBUS): introduction and methodology.

Authors:  Kari A O Tikkinen; Arnav Agarwal; Samantha Craigie; Rufus Cartwright; Michael K Gould; Jari Haukka; Richard Naspro; Giacomo Novara; Per Morten Sandset; Reed A Siemieniuk; Philippe D Violette; Gordon H Guyatt
Journal:  Syst Rev       Date:  2014-12-23

5.  Venous thromboembolism: A problem in the Indian/Asian population?

Authors:  Sunil Agarwal; Arvind Dhas Lee; Ravish Sanghi Raju; Edwin Stephen
Journal:  Indian J Urol       Date:  2009-01
  5 in total

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