Literature DB >> 15263223

Sparfloxacin, an antibacterial drug.

A Sivalakshmidevi1, K Vyas, G Om Reddy.   

Abstract

The title compound, sparfloxacin or cis-5-amino-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid trihydrate, C(19)H(22)F(2)N(4)O(3).3H(2)O, is an antibacterial drug. The molecule, which crystallizes as a trihydrate, is in the zwitterionic form in the solid state. Hydrogen bonds stabilize the molecules in the lattice.

Entities:  

Year:  2000        PMID： 15263223     DOI： 10.1107/S0108270100002523

Source DB:  PubMed          Journal:  Acta Crystallogr C        ISSN： 0108-2701            Impact factor:   1.172


  3 in total

1.  Bis[(2R,6S)-4-(5-amino-3-carb-oxy-1-cyclo-propyl-6,8-difluoro-4-oxo-1,4-dihydro-quinolin-7-yl)-2,6-dimethyl-piperazin-1-ium] sulfate penta-hydrate.

Authors:  Tao Li; Lin Yang; Yuan Cheng Wang; Qiang Lian
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-11-19

2.  Crystal structures of [Mn(bdc)(Hspar)2(H2O)0.25]·2H2O containing MnO6+1 capped trigonal prisms and [Cu(Hspar)2](bdc)·2H2O containing CuO4 squares (Hspar = sparfloxacin and bdc = benzene-1,4-di-carboxyl-ate).

Authors:  Zhe An; Jing Gao; William T A Harrison
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2016-01-01

3.  Biochemical Characterization of New Gemifloxacin Schiff Base (GMFX-o-phdn) Metal Complexes and Evaluation of Their Antimicrobial Activity against Some Phyto- or Human Pathogens.

Authors:  Hazem S Elshafie; Sadeek A Sadeek; Ippolito Camele; Amira A Mohamed
Journal:  Int J Mol Sci       Date:  2022-02-14       Impact factor: 5.923
  3 in total

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