Unilateral and bilateral surgery for parathyroid disease.

The principles of successful parathyroid surgery, regardless of the approach, demand a clear understanding of the philosophy behind the surgical exploration. A systematic approach, founded in science and refined by experience, is necessary to achieve long-term, reproducible surgical success. This article discusses the underlying logic and the advantages and disadvantages of the two basic approaches to parathyroid pathology: unilateral and bilateral cervical exploration. The authors do not to advocate a particular technique;instead, they provide a conceptual framework to surgical parathyroid disease upon which more advanced discussion can be built.