Literature DB >> 15261257

Synthesis and biological evaluation of novel 4"-alkoxy avermectin derivatives.

Kenichiro Nagai1, Kazuro Shiomi, Toshiaki Sunazuka, Achim Harder, Andreas Turberg, Satoshi Omura.   

Abstract

Novel 4"-alkoxy avermectin derivatives were synthesized via rhodium carbenoid mediated O-H insertion reaction and tested for antiparasite activity against Artemia salina and Caenorhabditis elegans.

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Year:  2004        PMID： 15261257     DOI： 10.1016/j.bmcl.2004.06.027

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Anthelmintic avermectins kill Mycobacterium tuberculosis, including multidrug-resistant clinical strains.

Authors:  Leah E Lim; Catherine Vilchèze; Carol Ng; William R Jacobs; Santiago Ramón-García; Charles J Thompson
Journal:  Antimicrob Agents Chemother       Date:  2012-11-19       Impact factor: 5.191

2.  Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases.

Authors:  Honami Yonezawa; Akari Ikeda; Ryo Takahashi; Haruka Endo; Yasuyo Sugawara; Mikako Goto; Mirute Kanno; Sosuke Ogawa; Karin Nakamura; Haruki Ujiie; Masato Iwatsuki; Tomoyasu Hirose; Toshiaki Sunazuka; Yoshimasa Uehara; Naoyuki Nishiya
Journal:  iScience       Date:  2022-03-07
  2 in total

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