| Literature DB >> 15260967 |
Abstract
Subcellular compartmentalization is an emerging paradigm in signaling pathways including the Ras/MAPK pathway. In a recent issue of Developmental Cell, Torii et al. (2004) characterize a new MAPK scaffold, Sef, that resides on the Golgi apparatus, binds active MEK/ERK complexes, and permits signaling to cytosolic substrates but not nuclear targets.Entities:
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Year: 2004 PMID： 15260967 DOI： 10.1016/j.molcel.2004.07.003
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970