Literature DB >> 1525928

Homeostasis as regulated by activated macrophage. V. Suppression of diabetes mellitus in non-obese diabetic mice by LPSw (a lipopolysaccharide from wheat flour).

M Iguchi1, H Inagawa, T Nishizawa, T Okutomi, A Morikawa, G I Soma, D Mizuno.   

Abstract

A lipopolysaccharide from wheat flour (LPSw) which was isolated and characterized is shown to exert definitely a suppressive effect on incidence of type 1 diabetes in mice. Therapeutic effect on type 2 diabetes in patients was also obtained, though only from preliminary results. The percutaneous route of administration is most favorable. The important role that precursor tumor necrosis factor, free or cell bound, may play in this mechanism is discussed.

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Year:  1992        PMID： 1525928     DOI： 10.1248/cpb.40.1004

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  11 in total

1.  99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: viruses, autoimmunity and immunoregulation.

Authors:  C M Filippi; M G von Herrath
Journal:  Clin Exp Immunol       Date:  2010-04       Impact factor: 4.330

2.  TLR2 signaling improves immunoregulation to prevent type 1 diabetes.

Authors:  Christophe M Filippi; Katrin Ehrhardt; Elizabeth A Estes; Par Larsson; Janine E Oldham; Matthias G von Herrath
Journal:  Eur J Immunol       Date:  2011-05       Impact factor: 5.532

Review 3.  99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: immune therapies of type 1 diabetes: new opportunities based on the hygiene hypothesis.

Authors:  L Chatenoud; S You; H Okada; C Kuhn; B Michaud; J-F Bach
Journal:  Clin Exp Immunol       Date:  2010-04       Impact factor: 4.330

4.  Genome sequence of Pantoea agglomerans strain IG1.

Authors:  Tomohiko Matsuzawa; Kazuki Mori; Takeshi Kadowaki; Misato Shimada; Kosuke Tashiro; Satoru Kuhara; Hiroyuki Inagawa; Gen-ichiro Soma; Kaoru Takegawa
Journal:  J Bacteriol       Date:  2012-03       Impact factor: 3.490

5.  A mixture of Salacia oblonga extract and IP-PA1 reduces fasting plasma glucose (FPG) and low-density lipoprotein (LDL) cholesterol levels.

Authors:  Kazue Nakata; Yoshie Taniguchi; Noriko Yoshioka; Aya Yoshida; Hiroyuki Inagawa; Takeru Nakamoto; Hiroshi Yoshimura; Shin-Ichiro Miyake; Chie Kohchi; Masahide Kuroki; Gen-Ichiro Soma
Journal:  Nutr Res Pract       Date:  2011-10-28       Impact factor: 1.926

Review 6.  Toll-Like Receptor Activation in Immunity vs. Tolerance in Autoimmune Diabetes.

Authors:  Elke Gülden; Li Wen
Journal:  Front Immunol       Date:  2014-03-24       Impact factor: 7.561

Review 7.  Immunotherapy of type 1 diabetes: lessons for other autoimmune diseases.

Authors:  Jean-François Bach
Journal:  Arthritis Res       Date:  2002-05-09

8.  Viral trigger for type 1 diabetes: pros and cons.

Authors:  Christophe M Filippi; Matthias G von Herrath
Journal:  Diabetes       Date:  2008-11       Impact factor: 9.461

9.  Pantoea agglomerans lipopolysaccharide maintains bone density in premenopausal women: a randomized, double-blind, placebo-controlled trial.

Authors:  Kazue Nakata; Yoko Nakata; Hiroyuki Inagawa; Takeru Nakamoto; Hiroshi Yoshimura; Gen-Ichiro Soma
Journal:  Food Sci Nutr       Date:  2014-07-16       Impact factor: 2.863

10.  Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents development of atherosclerosis in high-fat diet-fed apoE-deficient mice via ameliorating hyperlipidemia, pro-inflammatory mediators and oxidative responses.

Authors:  Yutaro Kobayashi; Hiroyuki Inagawa; Chie Kohchi; Kimiko Kazumura; Hiroshi Tsuchiya; Toshiyuki Miwa; Katsuichiro Okazaki; Gen-Ichiro Soma
Journal:  PLoS One       Date:  2018-03-27       Impact factor: 3.240
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