Literature DB >> 15258750

[Organ transplantation in human immunodeficiency virus-infected patients. Results of a survey in German transplantation centres].

N R Frühauf1, R Köditz, K Radecke, M Malagó, H Lang, C E Broelsch.   

Abstract

BACKGROUND: Despite considerable advances following the introduction of highly active antiretroviral therapy, organ transplantation is usually denied categorically for human immunodeficiency virus (HIV) patients, and it is presented in German transplantation law as a contraindication. Today, this should be questioned critically.
METHOD: A survey at all 87 German transplant centres was done concerning (1) how many HIV-positive patients were transplanted before and after February 2000, (2) willingness of the centres to transplant HIV-infected patients in the future, and (3) course of transplanted HIV patients so far.
RESULTS: With a response rate of 78%, 39% of the questioned centres were accepting HIV patients in the future for transplantation, and 39% rejected this. Twenty percent voted for individual case decision. Three centres had practiced liver transplantation in 11 patients.
CONCLUSION: The decision to transplant HIV-positive patients in Germany is mostly based on individual cases and not refused in general. However, prospective studies on this issue are justified and needed.

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Year:  2004        PMID: 15258750     DOI: 10.1007/s00104-004-0825-9

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  20 in total

Review 1.  Cardiovascular manifestations of HIV infection.

Authors:  Giuseppe Barbaro
Journal:  Circulation       Date:  2002-09-10       Impact factor: 29.690

2.  HIV testing in patients with end stage renal disease.

Authors:  A Stevens; J Little; S Kerr; P Kilbane; C Doherty
Journal:  BMJ       Date:  1990-02-17

3.  Infection with human immunodeficiency virus in the Pittsburgh transplant population. A study of 583 donors and 1043 recipients, 1981-1986.

Authors:  J S Dummer; S Erb; M K Breinig; M Ho; C R Rinaldo; P Gupta; M V Ragni; A Tzakis; L Makowka; D Van Thiel
Journal:  Transplantation       Date:  1989-01       Impact factor: 4.939

4.  Should all human immunodeficiency virus-infected patients with end-stage renal disease be excluded from transplantation? The views of U.S. transplant centers.

Authors:  A Spital
Journal:  Transplantation       Date:  1998-05-15       Impact factor: 4.939

5.  Liver transplantation in adults coinfected with HIV.

Authors:  A A Prachalias; A Pozniak; C Taylor; P Srinivasan; P Muiesan; J Wendon; M Cramp; R Williams; J O'Grady; M Rela; N D Heaton
Journal:  Transplantation       Date:  2001-11-27       Impact factor: 4.939

6.  Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.

Authors:  F J Palella; K M Delaney; A C Moorman; M O Loveless; J Fuhrer; G A Satten; D J Aschman; S D Holmberg
Journal:  N Engl J Med       Date:  1998-03-26       Impact factor: 91.245

7.  Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection.

Authors:  I Bica; B McGovern; R Dhar; D Stone; K McGowan; R Scheib; D R Snydman
Journal:  Clin Infect Dis       Date:  2001-01-23       Impact factor: 9.079

8.  The evaluation of candidates for renal transplantation. The current practice of U.S. transplant centers.

Authors:  E L Ramos; B L Kasiske; S R Alexander; G M Danovitch; W E Harmon; L Kahana; T J Kiresuk; J F Neylan
Journal:  Transplantation       Date:  1994-02-27       Impact factor: 4.939

9.  Effect of coadministered lopinavir and ritonavir (Kaletra) on tacrolimus blood concentration in liver transplantation patients.

Authors:  Ashokkumar B Jain; Raman Venkataramanan; Bijan Eghtesad; Amadeo Marcos; Margaret Ragni; Ron Shapiro; Ann B Rafail; John J Fung
Journal:  Liver Transpl       Date:  2003-09       Impact factor: 5.799

Review 10.  Human immunodeficiency virus infection in patients with solid-organ transplants: report of five cases and review.

Authors:  A Erice; F S Rhame; R C Heussner; D L Dunn; H H Balfour
Journal:  Rev Infect Dis       Date:  1991 Jul-Aug
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