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Literature DB >> 15257608

Biologically relevant chemical reactions of N7-alkylguanine residues in DNA.

Kent S Gates¹, Tony Nooner, Sanjay Dutta.

Abstract

Entities: Chemical

Mesh：

Substances：
DNA Adducts
Guanine

Year: 2004 PMID： 15257608 DOI： 10.1021/tx049965c

Source DB: PubMed Journal: Chem Res Toxicol ISSN： 0893-228X Impact factor: 3.739

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98 in total

1. An unprecedented nucleic acid capture mechanism for excision of DNA damage.

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2. DNA cleavage induced by antitumor antibiotic leinamycin and its biological consequences.

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3. Replication of the 2,6-diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeFapy-dGuo) adduct by eukaryotic DNA polymerases.

Authors: Plamen P Christov; Kinrin Yamanaka; Jeong-Yun Choi; Kei-ichi Takata; Richard D Wood; F Peter Guengerich; R Stephen Lloyd; Carmelo J Rizzo
Journal: Chem Res Toxicol Date: 2012-07-06 Impact factor: 3.739

4. Noncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.

Authors: Mostafa I Fekry; Jozsef Szekely; Sanjay Dutta; Leonid Breydo; Hong Zang; Kent S Gates
Journal: J Am Chem Soc Date: 2011-10-18 Impact factor: 15.419

5. Direct and Topoisomerase II Mediated DNA Damage by Bis-3-chloropiperidines: The Importance of Being an Earnest G.

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Journal: ChemMedChem Date: 2017-08-10 Impact factor: 3.466

6. Effect of N7-methylation on base pairing patterns of guanine: a DFT study.

Authors: Swarnadeep Biswas; Pradeep Kumar Shukla
Journal: J Mol Model Date: 2021-05-25 Impact factor: 1.810

7. Pathways of Metabolite-Related Damage to a Synthetic p53 Gene Exon 7 Oligonucleotide Using Magnetic Enzyme Bioreactor Beads and LC-MS/MS Sequencing.

Authors: Spundana Malla; Karteek Kadimisetty; Di Jiang; Dharamainder Choudhary; James F Rusling
Journal: Biochemistry Date: 2018-05-23 Impact factor: 3.162