Literature DB >> 1525732

Aqueous beclomethasone dipropionate nasal spray in the treatment of seasonal (ragweed) rhinitis.

E F Juniper1, D G Willms, G H Guyatt, P J Ferrie.   

Abstract

OBJECTIVES: To determine whether the provision of appropriate medication and comprehensive information before the ragweed pollen season enables patients to manage their hay fever successfully, achieving satisfactory symptom control and quality of life, to examine patient characteristics that may predict successful symptom management and to learn which factors patients consider when making treatment choices.
DESIGN: Single-group prospective cohort management study.
SUBJECTS: Ninety adults sensitive to ragweed pollen recruited from those who had participated in previous clinical studies and from those who responded to advertisements in the local media. INTERVENTION: Aqueous beclomethasone dipropionate nasal spray and comprehensive information about optimal therapy (starting before the ragweed pollen season and continued throughout at a dose of 400 micrograms/d) and how it may be used less intensively with an as-required regimen. MAIN OUTCOME MEASURES: Symptom control, patient satisfaction, quality of life and medication use.
RESULTS: More than 80% of the patients reported very good symptom control and were very satisfied. In all, 62% chose to use less than the optimal daily dose. Patients who had less than optimal symptom control used significantly less of the nasal spray than those with very good control either because they wanted to keep medication use to a minimum or because they were unable to remember to take their medication. The only significant predictor of inadequate control was an acknowledged inability to remember to take medication. Symptoms and trust in the practitioner were the primary factors perceived by the patients to determine their treatment choices.
CONCLUSION: When provided with aqueous beclomethasone dipropionate nasal spray and comprehensive information on the drug and dosing, most patients are successful in managing their hay fever.

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Year:  1992        PMID: 1525732      PMCID: PMC1336335     

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  3 in total

1.  Aqueous beclomethasone diproprionate nasal spray: regular versus "as required" use in the treatment of seasonal allergic rhinitis.

Authors:  E F Juniper; G H Guyatt; P M O'Byrne; M Viveiros
Journal:  J Allergy Clin Immunol       Date:  1990-09       Impact factor: 10.793

2.  Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis.

Authors:  E F Juniper; G H Guyatt
Journal:  Clin Exp Allergy       Date:  1991-01       Impact factor: 5.018

3.  A comparison of budesonide and beclomethasone dipropionate nasal aerosols in ragweed-induced rhinitis.

Authors:  M A Vanzieleghem; E F Juniper
Journal:  J Allergy Clin Immunol       Date:  1987-06       Impact factor: 10.793

  3 in total
  5 in total

Review 1.  Economic outcomes for the treatment of allergic rhinitis.

Authors:  C M Kozma; M K Sadik; M L Watrous
Journal:  Pharmacoeconomics       Date:  1996-07       Impact factor: 4.981

2.  Development and preliminary validation of the multiattribute Rhinitis Symptom Utility Index.

Authors:  D A Revicki; N K Leidy; F Brennan-Diemer; C Thompson; A Togias
Journal:  Qual Life Res       Date:  1998-12       Impact factor: 4.147

Review 3.  Impact of allergic rhinitis treatment on quality of life.

Authors:  A Tripathi; R Patterson
Journal:  Pharmacoeconomics       Date:  2001       Impact factor: 4.981

4.  Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.

Authors:  Daniel J Glass; Anne S Harper
Journal:  BMC Fam Pract       Date:  2003-08-13       Impact factor: 2.497

5.  β-Glucan supplementation, allergy symptoms, and quality of life in self-described ragweed allergy sufferers.

Authors:  Shawn M Talbott; Julie A Talbott; Tracy L Talbott; Elaine Dingler
Journal:  Food Sci Nutr       Date:  2014-01-08       Impact factor: 2.863

  5 in total

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