Devastating endophthalmitis caused by Serratia marcescens in two recipients after transplantation of corneal grafts from the same donor.

We report two cases of severe endophthalmitis, which were caused by Serratia marcescens, and developed in the immediate postoperative period in two recipients of corneal grafts from the same donor. The cause of the donor's death was massive CVA. He had been on mechanical ventilation for 12 days before he died, and had shown no sign of infectious disease while in the hospital. Vitrectomies were performed in the recipients' eyes on the third day after corneal transplantation. On the same day, and again 1day later, the transplanted eyes were injected intravitreally with vancomycin and ceftazidime. Two months after surgery, both eyes developed phthisis. These cases are similar to other rare reported cases describing the virulence of S. marcescens.