Literature DB >> 15256699

New cholinesterase inhibiting bisbenzylisoquinoline alkaloids from Cocculus pendulus.

Sarfraz Ahmad Nawaz, Iqbal M Choudhary.   

Abstract

Phytochemical investigation on Cocculus pendulus (J. R. & G. FORST.) resulted in the isolation of two new and three known bisbenzylisoquinoline alkaloids. The structures of the new alkaloids, kurramine-2'-beta-N-oxide (1) and kurramine-2'-alpha-N-oxide (2), were elucidated with the help of spectroscopic techniques. The cholinesterase inhibitory activities of these bisbenzylisoquinoline alkaloids are reported here for the first time.

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Year:  2004        PMID： 15256699     DOI： 10.1248/cpb.52.802

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  7 in total

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