Literature DB >> 15256241

Limitation of diagnostic laparoscopy for patients with a periampullary carcinoma.

E H B M Tilleman1, B W Kuiken, S S K S Phoa, S M M de Castro, O R C Busch, H Obertop, D J Gouma.   

Abstract

BACKGROUND: Diagnostic laparoscopy has been generally accepted in staging of patients with a periampullary malignancy. In our institution diagnostic laparoscopy was routinely used since 1992. However, in 1998 it was eliminated from the protocol since in a prospective study a yield of only 13% was found with a histologically proven accuracy of 60% for distant metastases. The effect of implementation of the new protocol on the occurrence of unnecessary laparotomies and the outcome after bypass surgery was assessed.
METHODS: Between January 1999 and December 2001, 186 consecutive patients with a potentially resectable periampullary carcinoma after radiological staging without diagnostic laparoscopy underwent explorative laparotomy with the intention to perform a curative pancreatoduodenectomy. Incidence of unresectability and outcome of palliative surgery were assessed.
RESULTS: Resection could not be performed in 65 patients who underwent laparotomy because of metastatic disease (29 patients) and loco-regional tumour ingrowth (34 patients). These patients underwent a bypass procedure with a median survival of 216 days.
CONCLUSION: At laparotomy distant metastases were detected in 16% of the patients. Considering the fact that the detection rate of diagnostic laparoscopy is lower than 100%, the use of staging laparotomy is too limited to justify it as a routine procedure.

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Year:  2004        PMID: 15256241     DOI: 10.1016/j.ejso.2004.03.019

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  6 in total

1.  Predicting distant metastasis in patients with suspected pancreatic and periampullary tumors for selective use of staging laparoscopy.

Authors:  Annelie Slaar; Wietse J Eshuis; Niels A van der Gaag; C Yung Nio; Olivier R C Busch; Thomas M van Gulik; Johannes B Reitsma; Dirk J Gouma
Journal:  World J Surg       Date:  2011-11       Impact factor: 3.352

2.  Assessment of pancreatic malignancy with laparoscopy and intraoperative ultrasound.

Authors:  H Doucas; C D Sutton; A Zimmerman; A R Dennison; D P Berry
Journal:  Surg Endosc       Date:  2006-12-20       Impact factor: 4.584

3.  Staging laparoscopy for proximal pancreatic cancer in a magnetic resonance imaging-driven practice: what's it worth?

Authors:  Elliot Tapper; Bobby Kalb; Diego R Martin; David Kooby; N Volkan Adsay; Juan M Sarmiento
Journal:  HPB (Oxford)       Date:  2011-08-19       Impact factor: 3.647

4.  Is there still a role for laparoscopy combined with laparoscopic ultrasonography in the staging of pancreatic cancer?

Authors:  Matteo Barabino; Roberto Santambrogio; Andrea Pisani Ceretti; Rocco Scalzone; Marco Montorsi; Enrico Opocher
Journal:  Surg Endosc       Date:  2010-06-22       Impact factor: 4.584

Review 5.  Review of the investigation and surgical management of resectable ampullary adenocarcinoma.

Authors:  James Askew; Saxon Connor
Journal:  HPB (Oxford)       Date:  2013-01-10       Impact factor: 3.647

Review 6.  Diagnostic accuracy of laparoscopy following computed tomography (CT) scanning for assessing the resectability with curative intent in pancreatic and periampullary cancer.

Authors:  Victoria B Allen; Kurinchi Selvan Gurusamy; Yemisi Takwoingi; Amun Kalia; Brian R Davidson
Journal:  Cochrane Database Syst Rev       Date:  2016-07-06
  6 in total

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