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Literature DB >> 15254582

Innate immunity dictates cytokine polarization relevant to the development of pulmonary fibrosis.

Abstract

New data support the importance of the innate immune response in the resolution or progression of pulmonary fibrosis. The presence of CXC chemokine receptor 3-expressing cells, specifically pulmonary NK cells, is necessary to produce IFN-gamma. This is critical in the polarization of the immune response to injury toward a favorable Th1 response and resolution. In contrast, a Th2 response is associated with progressive fibrosis.

Entities: Disease Gene

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Year: 2004 PMID： 15254582 PMCID： PMC449755 DOI： 10.1172/JCI22398

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

17 in total

Review 1. American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS).

Authors:
Journal: Am J Respir Crit Care Med Date: 2000-02 Impact factor: 21.405

Review 2. American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001.

Authors:
Journal: Am J Respir Crit Care Med Date: 2002-01-15 Impact factor: 21.405

3. Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia.

Authors: Gary W Hunninghake; David A Lynch; Jeffrey R Galvin; Barry H Gross; Nestor Müller; David A Schwartz; Talmadge E King; Joseph P Lynch; Richard Hegele; James Waldron; Thomas V Colby; James C Hogg
Journal: Chest Date: 2003-10 Impact factor: 9.410

Review 4. The prognosis of idiopathic pulmonary fibrosis.

Authors: Andrew Perez; Robert M Rogers; James H Dauber
Journal: Am J Respir Cell Mol Biol Date: 2003-09 Impact factor: 6.914

5. Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling.

Authors: R L Rabin; M K Park; F Liao; R Swofford; D Stephany; J M Farber
Journal: J Immunol Date: 1999-04-01 Impact factor: 5.422

6. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans.

Authors: Fengrong Zuo; Naftali Kaminski; Elsie Eugui; John Allard; Zohar Yakhini; Amir Ben-Dor; Lance Lollini; David Morris; Yong Kim; Barbara DeLustro; Dean Sheppard; Annie Pardo; Moises Selman; Renu A Heller
Journal: Proc Natl Acad Sci U S A Date: 2002-04-30 Impact factor: 11.205

7. A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis.

Authors: R Ziesche; E Hofbauer; K Wittmann; V Petkov; L H Block
Journal: N Engl J Med Date: 1999-10-21 Impact factor: 91.245

8. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis.

Authors: Ganesh Raghu; Kevin K Brown; Williamson Z Bradford; Karen Starko; Paul W Noble; David A Schwartz; Talmadge E King
Journal: N Engl J Med Date: 2004-01-08 Impact factor: 91.245

9. Effects of interferon-gamma 1b on biomarker expression in patients with idiopathic pulmonary fibrosis.

Authors: Robert M Strieter; Karen M Starko; Richard I Enelow; Imre Noth; Vincent G Valentine
Journal: Am J Respir Crit Care Med Date: 2004-03-24 Impact factor: 21.405

Review 10. Interferon-gamma: an overview of signals, mechanisms and functions.

Authors: Kate Schroder; Paul J Hertzog; Timothy Ravasi; David A Hume
Journal: J Leukoc Biol Date: 2003-10-02 Impact factor: 4.962

13 in total

1. Protective role of NKT cells and macrophage M2-driven phenotype in bleomycin-induced pulmonary fibrosis.

Authors: Felipe Grabarz; Cristhiane Favero Aguiar; Matheus Correa-Costa; Tárcio Teodoro Braga; Meire I Hyane; Vinícius Andrade-Oliveira; Maristella Almeida Landgraf; Niels Olsen Saraiva Câmara
Journal: Inflammopharmacology Date: 2017-08-04 Impact factor: 4.473

Innate immunity dictates cytokine polarization relevant to the development of pulmonary fibrosis.

Review 1. American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS).

3. Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia.

Review 4. The prognosis of idiopathic pulmonary fibrosis.

5. Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling.

6. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans.

7. A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis.

8. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis.

9. Effects of interferon-gamma 1b on biomarker expression in patients with idiopathic pulmonary fibrosis.

Review 10. Interferon-gamma: an overview of signals, mechanisms and functions.

1. Protective role of NKT cells and macrophage M2-driven phenotype in bleomycin-induced pulmonary fibrosis.

Review 2. Transgenic modelling of cytokine polarization in the lung.

Review 3. Maintenance of radiation-induced intestinal fibrosis: cellular and molecular features.

Review 4. Natural killer cells in infection and inflammation of the lung.

5. Inflammatory mechanisms in the lung.

6. CD8+ T lymphocytes in lung tissue from patients with idiopathic pulmonary fibrosis.

7. Interleukin-12 is not essential for silicosis in mice.

8. Galectin-3 regulates myofibroblast activation and hepatic fibrosis.

9. Mechanisms of over-activated innate immune system regulation in autoimmune and neurodegenerative disorders.

Review 10. The interplay of DAMPs, TLR4, and proinflammatory cytokines in pulmonary fibrosis.