Literature DB >> 15252224

[Experimental analysis of therapeutic properties of Rhodiola rosea L. and its possible application in medicine].

Agne Kucinskaite1, Vitalis Briedis, Arūnas Savickas.   

Abstract

The paper presents a review of the scientific publications on Rhodiola rosea L. known for its adaptogenic characteristics. Biologically active substances salidroside, rosin, rosavin, rosarin and tyrosol, which are mainly found in plant rhizomes, demonstrate therapeutic effect. These active components effect the central nervous system by increasing the ability to concentrate, the mental and physical power; they are efficient in the asthenic states and improve general resistance of the cells and the organism against the harmful outer influence. They also prevent the heart system from stress and arrhythmias, and posses some antioxidant activity. Some data confirm that the Rhodiola rosea L. preparations stop the growth of the malignant tumors and metastases in the liver. Some preclinical and clinical data of the golden root preparations are discussed in the survey. The interaction of the herb with other medicines, its usage and effect, recommended doses, and its side effects are also reviewed in the paper.

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Year:  2004        PMID: 15252224

Source DB:  PubMed          Journal:  Medicina (Kaunas)        ISSN: 1010-660X            Impact factor:   2.430


  20 in total

Review 1.  Astonishing diversity of natural surfactants: 5. Biologically active glycosides of aromatic metabolites.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-09       Impact factor: 1.880

2.  Neuroprotection against cobalt chloride-induced cell apoptosis of primary cultured cortical neurons by salidroside.

Authors:  Shuqiang Zhang; Xia Chen; Yumin Yang; Xinyang Zhou; Jie Liu; Fei Ding
Journal:  Mol Cell Biochem       Date:  2011-04-17       Impact factor: 3.396

3.  Effects of Salidroside on Myocardial Injury In Vivo In Vitro via Regulation of Nox/NF-κB/AP1 Pathway.

Authors:  Lingpeng Zhu; Tingting Wei; Xiayun Chang; He He; Jin Gao; Zhengli Wen; Tianhua Yan
Journal:  Inflammation       Date:  2015-08       Impact factor: 4.092

4.  Salidroside attenuates LPS-stimulated activation of THP-1 cell-derived macrophages through down-regulation of MAPK/NF-kB signaling pathways.

Authors:  Hong-Wu Wang; Ting Wu; Jun-Ying Qi; Ya-Qi Wang; Xiao-Ping Luo; Qin Ning
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2013-08-01

5.  Neuroprotective effects of Salidroside and its analogue tyrosol galactoside against focal cerebral ischemia in vivo and H2O2-induced neurotoxicity in vitro.

Authors:  Tian-yao Shi; Shu-fang Feng; Jiang-hao Xing; Yu-mei Wu; Xiao-qiang Li; Nan Zhang; Zhen Tian; Shui-bing Liu; Ming-gao Zhao
Journal:  Neurotox Res       Date:  2011-11-18       Impact factor: 3.911

6.  Binding to WGR domain by salidroside activates PARP1 and protects hematopoietic stem cells from oxidative stress.

Authors:  Xue Li; Ozlem Erden; Liang Li; Qidong Ye; Andrew Wilson; Wei Du
Journal:  Antioxid Redox Signal       Date:  2014-03-05       Impact factor: 8.401

7.  Involvement of ERK1/2 pathway in neuroprotection by salidroside against hydrogen peroxide-induced apoptotic cell death.

Authors:  Shu Yu; Yuntian Shen; Jie Liu; Fei Ding
Journal:  J Mol Neurosci       Date:  2009-09-29       Impact factor: 3.444

8.  Neuroprotective effects of salidroside in the PC12 cell model exposed to hypoglycemia and serum limitation.

Authors:  Shu Yu; Mei Liu; Xiaosong Gu; Fei Ding
Journal:  Cell Mol Neurobiol       Date:  2008-05-15       Impact factor: 5.046

9.  Protective effect of salidroside against H2O2-induced cell apoptosis in primary culture of rat hippocampal neurons.

Authors:  Xia Chen; Qi Zhang; Qiong Cheng; Fei Ding
Journal:  Mol Cell Biochem       Date:  2009-06-25       Impact factor: 3.396

10.  The role of biotechnology for conservation and biologically active substances production of Rhodiola rosea: endangered medicinal species.

Authors:  Krasimira Tasheva; Georgina Kosturkova
Journal:  ScientificWorldJournal       Date:  2012-04-30
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