Literature DB >> 15251198

The streptococcolytic enzyme zoocin A is a penicillin-binding protein.

Lucie S Heath1, Harry E Heath, Paul A LeBlanc, S Rochelle Smithberg, Muriel Dufour, Robin S Simmonds, Gary L Sloan.   

Abstract

Zoocin A is a streptococcolytic enzyme produced by Streptococcus equi subsp. zooepidemicus 4881 that has an unknown site of action on the peptidoglycans of susceptible organisms. Analysis of a mutant strain in which the genes for zoocin A and resistance to zoocin A were inactivated revealed that this strain was more susceptible to beta-lactam antibiotics than the parental organism. Purified zoocin A had weak beta-lactamase activity, bound radioactive penicillin covalently, and its streptococcolytic activity was inhibited by penicillin. Thus, zoocin A is a penicillin-binding protein and presumably is a D-alanyl endopeptidase.

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Year:  2004        PMID： 15251198     DOI： 10.1016/j.femsle.2004.05.038

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  10 in total

1.  Characterization of a novel family of fibronectin-binding proteins with M23 peptidase domains from Treponema denticola.

Authors:  C V Bamford; T Francescutti; C E Cameron; H F Jenkinson; D Dymock
Journal:  Mol Oral Microbiol       Date:  2010-12       Impact factor: 3.563

2.  Association of a D-alanyl-D-alanine carboxypeptidase gene with the formation of aberrantly shaped cells during the induction of viable but nonculturable Vibrio parahaemolyticus.

Authors:  Wei-cheng Hung; Wann-Neng Jane; Hin-chung Wong
Journal:  Appl Environ Microbiol       Date:  2013-09-20       Impact factor: 4.792

3.  The metal binding site of zoocin A.

Authors:  Yinghua Chen; Robin S Simmonds; Gary L Sloan; Russell Timkovich
Journal:  J Biol Inorg Chem       Date:  2008-04-03       Impact factor: 3.358

4.  Zif, the zoocin A immunity factor, is a FemABX-like immunity protein with a novel mode of action.

Authors:  Shaw R Gargis; Amy S Gargis; Harry E Heath; Lucie S Heath; Paul A LeBlanc; Maria M Senn; Brigitte Berger-Bächi; Robin S Simmonds; Gary L Sloan
Journal:  Appl Environ Microbiol       Date:  2009-08-14       Impact factor: 4.792

5.  Use of 4-sulfophenyl isothiocyanate labeling and mass spectrometry to determine the site of action of the streptococcolytic peptidoglycan hydrolase zoocin A.

Authors:  Shaw R Gargis; Harry E Heath; Lucie S Heath; Paul A Leblanc; Robin S Simmonds; Brian D Abbott; Russell Timkovich; Gary L Sloan
Journal:  Appl Environ Microbiol       Date:  2008-10-31       Impact factor: 4.792

6.  The CiaR response regulator in group B Streptococcus promotes intracellular survival and resistance to innate immune defenses.

Authors:  Darin Quach; Nina M van Sorge; Sascha A Kristian; Joshua D Bryan; Daniel W Shelver; Kelly S Doran
Journal:  J Bacteriol       Date:  2008-12-29       Impact factor: 3.490

7.  Isolation and Characterization of Strain Exiguobacterium sp. KRL4, a Producer of Bioactive Secondary Metabolites from a Tibetan Glacier.

Authors:  Pietro Tedesco; Fortunato Palma Esposito; Antonio Masino; Giovanni Andrea Vitale; Emiliana Tortorella; Annarita Poli; Barbara Nicolaus; Leonardo Joaquim van Zyl; Marla Trindade; Donatella de Pascale
Journal:  Microorganisms       Date:  2021-04-21

8.  Diversity of bacteriocins in the microbiome of the Tucuruí Hydroelectric Power Plant water reservoir and three-dimensional structure prediction of a zoocin.

Authors:  Sávio S Costa; Leticia A B Lago; Artur Silva; Diego A das Graças; Jerônimo Lameira; Rafael A Baraúna
Journal:  Genet Mol Biol       Date:  2022-01-05       Impact factor: 1.771

9.  Parallel Evolution of Group B Streptococcus Hypervirulent Clonal Complex 17 Unveils New Pathoadaptive Mutations.

Authors:  Alexandre Almeida; Isabelle Rosinski-Chupin; Céline Plainvert; Pierre-Emmanuel Douarre; Maria J Borrego; Claire Poyart; Philippe Glaser
Journal:  mSystems       Date:  2017-09-05       Impact factor: 6.496

10.  Bacteriocin Producing Streptococcus agalactiae Strains Isolated from Bovine Mastitis in Brazil.

Authors:  João Ricardo Vidal Amaral; Rommel Thiago Jucá Ramos; Fabrício Almeida Araújo; Rodrigo Bentes Kato; Flávia Figueira Aburjaile; Siomar de Castro Soares; Aristóteles Góes-Neto; Mateus Matiuzzi da Costa; Vasco Azevedo; Bertram Brenig; Selma Soares de Oliveira; Alexandre Soares Rosado
Journal:  Microorganisms       Date:  2022-03-09
  10 in total

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