Photodynamic therapy for subungual Bowen's disease.

A 35-year-old police shooting instructor with a 4-year history of Bowen's disease of the nail bed on his right index finger confirmed histologically, was successfully treated with photodynamic therapy (PDT). Four cycles of PDT were used with two different photosensitizers: 20% 5-amino-levulinic acid oil in water emulsion and methyl amino-levulinate (Metvix) cream. The lesion was successfully treated with clinical and histological clearance. There was minimal loss of time from work, with neither functional nor cosmetic deficits.