Literature DB >> 15250689

X-ray crystal structure and EPR spectra of "arsenite-inhibited" Desulfovibriogigas aldehyde dehydrogenase: a member of the xanthine oxidase family.

D Roeland Boer1, Anders Thapper, Carlos D Brondino, Maria J Romão, José J G Moura.   

Abstract

X-ray crystallography has been used to determine the structure of arsenite-inhibited aldehyde dehydrogenase from Desulfovibrio gigas, a member of the xanthine oxidase family of mononuclear molybdenum enzymes. The structure shows an AsO3 moiety bound to the molybdenum atom of the active site through one of the oxygen atoms. A reduced sample of arsenite-inhibited aldehyde dehydrogenase has a Mo(V) signal that shows anisotropic hyperfine and quadrupole coupling to one arsenic atom. This signal has a strong resemblance with a previously reported signal for arsenite-inhibited xanthine oxidase.

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Year:  2004        PMID： 15250689     DOI： 10.1021/ja0490222

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  9 in total

1.  On the purification and preliminary crystallographic analysis of isoquinoline 1-oxidoreductase from Brevundimonas diminuta 7.

Authors:  D Roeland Boer; Axel Müller; Susanne Fetzner; David J Lowe; Maria João Romão
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2004-12-24

Review 2.  The mononuclear molybdenum enzymes.

Authors:  Russ Hille; James Hall; Partha Basu
Journal:  Chem Rev       Date:  2014-01-28       Impact factor: 60.622

3.  Isotropic exchange interaction between Mo and the proximal FeS center in the xanthine oxidase family member aldehyde oxidoreductase from Desulfovibrio gigas on native and polyalcohol inhibited samples: an EPR and QM/MM study.

Authors:  María C Gómez; Nicolás I Neuman; Sergio D Dalosto; Pablo J González; José J G Moura; Alberto C Rizzi; Carlos D Brondino
Journal:  J Biol Inorg Chem       Date:  2014-10-25       Impact factor: 3.358

4.  Xanthine oxidase-product complexes probe the importance of substrate/product orientation along the reaction coordinate.

Authors:  Jing Yang; Chao Dong; Martin L Kirk
Journal:  Dalton Trans       Date:  2017-10-10       Impact factor: 4.390

5.  X-ray crystal structure of arsenite-inhibited xanthine oxidase: μ-sulfido,μ-oxo double bridge between molybdenum and arsenic in the active site.

Authors:  Hongnan Cao; James Hall; Russ Hille
Journal:  J Am Chem Soc       Date:  2011-07-21       Impact factor: 15.419

6.  Molybdenum and Tungsten Cofactors and the Reactions They Catalyze.

Authors:  Martin L Kirk; Khadanand Kc
Journal:  Met Ions Life Sci       Date:  2020-03-23

7.  Structural and mechanistic analysis of the arsenate respiratory reductase provides insight into environmental arsenic transformations.

Authors:  Nathaniel R Glasser; Paul H Oyala; Thomas H Osborne; Joanne M Santini; Dianne K Newman
Journal:  Proc Natl Acad Sci U S A       Date:  2018-08-13       Impact factor: 11.205

8.  Correlating EPR and X-ray structural analysis of arsenite-inhibited forms of aldehyde oxidoreductase.

Authors:  Anders Thapper; D R Boer; Carlos D Brondino; José J G Moura; Maria J Romão
Journal:  J Biol Inorg Chem       Date:  2006-12-01       Impact factor: 3.862

Review 9.  Mutations associated with functional disorder of xanthine oxidoreductase and hereditary xanthinuria in humans.

Authors:  Kimiyoshi Ichida; Yoshihiro Amaya; Ken Okamoto; Takeshi Nishino
Journal:  Int J Mol Sci       Date:  2012-11-21       Impact factor: 5.923
  9 in total

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