Literature DB >> 1525062

Progestin-induced fatty acid synthetase in human mammary tumors: from molecular to clinical studies.

D Chalbos1, C Joyeux, F Galtier, H Rochefort.   

Abstract

Fatty acid synthetase (FAS) is one of the first well-characterized progestin-induced proteins with available antibodies and cDNA. This paper reviews basic studies on FAS regulation in human breast cancer cell lines and recent data on the possible clinical significance of this new marker of hormone responsiveness in mammary cancer and benign breast diseases.

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Year:  1992        PMID： 1525062     DOI： 10.1016/0960-0760(92)90211-z

Source DB:  PubMed          Journal:  J Steroid Biochem Mol Biol        ISSN： 0960-0760            Impact factor:   4.292


  11 in total

1.  TReP-132 is a novel progesterone receptor coactivator required for the inhibition of breast cancer cell growth and enhancement of differentiation by progesterone.

Authors:  Florence Gizard; Romain Robillard; Barbara Gross; Olivier Barbier; Françoise Révillion; Jean-Philippe Peyrat; Gérard Torpier; Dean W Hum; Bart Staels
Journal:  Mol Cell Biol       Date:  2006-10       Impact factor: 4.272

2.  3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers.

Authors:  Dylan T Jones; Alessandro Valli; Syed Haider; Qifeng Zhang; Elizabeth A Smethurst; Zachary T Schug; Barrie Peck; Eric O Aboagye; Susan E Critchlow; Almut Schulze; Eyal Gottlieb; Michael J O Wakelam; Adrian L Harris
Journal:  Mol Cancer Ther       Date:  2018-11-26       Impact factor: 6.261

3.  Fatty Acid Synthase and Acetyl-CoA Carboxylase Are Expressed in Nodal Metastatic Melanoma But Not in Benign Intracapsular Nodal Nevi.

Authors:  Jad Saab; Maria Laureana Santos-Zabala; Massimo Loda; Edward C Stack; Travis J Hollmann
Journal:  Am J Dermatopathol       Date:  2018-04       Impact factor: 1.533

4.  Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia.

Authors:  A Rashid; E S Pizer; M Moga; L Z Milgraum; M Zahurak; G R Pasternack; F P Kuhajda; S R Hamilton
Journal:  Am J Pathol       Date:  1997-01       Impact factor: 4.307

5.  Raman and coherent anti-Stokes Raman scattering microscopy studies of changes in lipid content and composition in hormone-treated breast and prostate cancer cells.

Authors:  Mariana C Potcoava; Gregory L Futia; Jessica Aughenbaugh; Isabel R Schlaepfer; Emily A Gibson
Journal:  J Biomed Opt       Date:  2014       Impact factor: 3.170

6.  The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism.

Authors:  J T Moncur; J P Park; V A Memoli; T K Mohandas; W B Kinlaw
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-09       Impact factor: 11.205

7.  Metformin-induced killing of triple-negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193b.

Authors:  Reema S Wahdan-Alaswad; Dawn R Cochrane; Nicole S Spoelstra; Erin N Howe; Susan M Edgerton; Steven M Anderson; Ann D Thor; Jennifer K Richer
Journal:  Horm Cancer       Date:  2014-09-12       Impact factor: 3.869

8.  Raman Microscopy Techniques to Study Lipid Droplet Composition in Cancer Cells.

Authors:  Mariana C Potcoava; Gregory L Futia; Emily A Gibson; Isabel R Schlaepfer
Journal:  Methods Mol Biol       Date:  2022

9.  Fatty acid synthase regulates estrogen receptor-α signaling in breast cancer cells.

Authors:  J A Menendez; R Lupu
Journal:  Oncogenesis       Date:  2017-02-27       Impact factor: 7.485

Review 10.  An Overview of Lipid Droplets in Cancer and Cancer Stem Cells.

Authors:  L Tirinato; F Pagliari; T Limongi; M Marini; A Falqui; J Seco; P Candeloro; C Liberale; E Di Fabrizio
Journal:  Stem Cells Int       Date:  2017-08-13       Impact factor: 5.443
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