Literature DB >> 15249969

[Suicidal fatal beta-blocker intoxication].

P Hilbert1, K Zur Nieden.   

Abstract

We report on the case of a 45-year-old female with beta receptor antagonist intoxication after swallowing about 30 tablets of Cordanum (Talinolol) with suicidal intent. The out of hospital and clinical management is discussed. Prior to admission to hospital the patient only showed a few signs of intoxication such as hypotension, central symptoms and cyanosis. There was no bradycardia but during treatment she developed cardiac arrest. Out of hospital it was possible to stabilise the circulation with catecholamines (norepinephrin) and the transport to hospital was uneventful but only a few minutes after hospital admission the patient developed cardiac arrest. After initially successful CPR the patient died some hours later in the intensive care unit.

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Year:  2004        PMID: 15249969     DOI: 10.1007/s00101-004-0721-1

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  4 in total

1.  Pharmacokinetics of oral talinolol following a single dose and during steady state in patients with chronic renal failure and healthy volunteers.

Authors:  M Krueger; H Achenbach; B Terhaag; H Haase; K Richter; R Oertel; R Preiss
Journal:  Int J Clin Pharmacol Ther       Date:  2001-02       Impact factor: 1.366

2.  Calcium and beta receptor antagonist overdose: a review and update of pharmacological principles and management.

Authors:  Christopher R H Newton; Joao H Delgado; Hernan F Gomez
Journal:  Semin Respir Crit Care Med       Date:  2002-02       Impact factor: 3.119

Review 3.  Modulation of beta-adrenergic receptor subtype activities in perioperative medicine: mechanisms and sites of action.

Authors:  M Zaugg; M C Schaub; T Pasch; D R Spahn
Journal:  Br J Anaesth       Date:  2002-01       Impact factor: 9.166

4.  [Acute beta 1-selective beta-receptor blocker nebivolol poisoning in attempted suicide].

Authors:  K M Heinroth; C Kuhn; R Walper; I Busch; M Winkler; R Prondzinsky
Journal:  Dtsch Med Wochenschr       Date:  1999-10-22       Impact factor: 0.628

  4 in total

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