BACKGROUND: Polypoid lesions of the gallbladder encompass a wide variety of pathology. Although most of these lesions are benign, some early carcinomas of the gallbladder do present as polypoid lesions. Problems remain in selecting patients with polypoid lesions of the gallbladder for surgery, the operative approach, and the method of follow-up of those deemed not needing surgery. DATA SOURCES: This review was done by Medline search of the English literature by the keywords "polypoid lesions of gallbladder," "gallbladder polyps," "carcinoma of gallbladder," and "benign tumors of gallbladder." CONCLUSIONS: Most small polypoid lesions of the gallbladder are benign and remain static for years. Three- to six-monthly ultrasonography examination is warranted in the initial follow-up period but it is probably unnecessary after 1 or 2 years. Age more than 50 years and size of polyp more than 1 cm are the two most important factors predicting malignancy in polypoid lesions of the gallbladder. Other risk factors include concurrent gallstones, solitary polyp, and symptomatic polyp. Laparoscopic cholecystectomy is the treatment of choice unless the suspicion of malignancy is high, in which case it is advisable to have open exploration, intraoperative frozen section, and preparation for extended resection.
BACKGROUND: Polypoid lesions of the gallbladder encompass a wide variety of pathology. Although most of these lesions are benign, some early carcinomas of the gallbladder do present as polypoid lesions. Problems remain in selecting patients with polypoid lesions of the gallbladder for surgery, the operative approach, and the method of follow-up of those deemed not needing surgery. DATA SOURCES: This review was done by Medline search of the English literature by the keywords "polypoid lesions of gallbladder," "gallbladder polyps," "carcinoma of gallbladder," and "benign tumors of gallbladder." CONCLUSIONS: Most small polypoid lesions of the gallbladder are benign and remain static for years. Three- to six-monthly ultrasonography examination is warranted in the initial follow-up period but it is probably unnecessary after 1 or 2 years. Age more than 50 years and size of polyp more than 1 cm are the two most important factors predicting malignancy in polypoid lesions of the gallbladder. Other risk factors include concurrent gallstones, solitary polyp, and symptomatic polyp. Laparoscopic cholecystectomy is the treatment of choice unless the suspicion of malignancy is high, in which case it is advisable to have open exploration, intraoperative frozen section, and preparation for extended resection.
Authors: B J G A Corten; S Alexander; P H van Zwam; W K G Leclercq; R M H Roumen; G D Slooter Journal: J Gastrointest Surg Date: 2018-08-21 Impact factor: 3.452
Authors: Joo Kyung Park; Yong Bum Yoon; Yong-Tae Kim; Ji Kon Ryu; Won Jae Yoon; Sang Hyub Lee; Su-Jong Yu; Hae Yeon Kang; Jae Young Lee; Min Jung Park Journal: Gut Liver Date: 2008-09-30 Impact factor: 4.519
Authors: Seon Hee Lim; Dong Hee Kim; Min Jung Park; Young Sun Kim; Chung Hyun Kim; Jung Yun Yim; Kyung Ran Cho; Sun Sin Kim; Seung Ho Choi; Nayoung Kim; Sang Heon Cho; Byung-Hee Oh Journal: Gut Liver Date: 2007-12-31 Impact factor: 4.519
Authors: Young Koog Cheon; Won Young Cho; Tae Hee Lee; Young Deok Cho; Jong Ho Moon; Joon Seong Lee; Chan Sup Shim Journal: World J Gastroenterol Date: 2009-05-21 Impact factor: 5.742