| Literature DB >> 15249204 |
Bhakti Joshi1, Roland Schmid, Karlheinz Altendorf, Shree Kumar Apte.
Abstract
Exposure to 6kGy dose of (60)Co gamma-rays resulted in immediate growth arrest, followed by complete recovery of Deinococcus radiodurans strain R1 cells. Selective degradation and resynthesis of several predicted highly expressed proteins (including major chaperones, key TCA cycle enzymes, and few stress proteins) and several hypothetical proteins marked the lag period, preceding resumption of growth. A major exercise in protein recycling appears to be an integral component of post-irradiation recovery in D. radiodurans and complements the extensive DNA repair, characteristic of this extremely radioresistant bacterium.Entities:
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Year: 2004 PMID： 15249204 DOI： 10.1016/j.bbrc.2004.06.062
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575