Literature DB >> 15248469

Trypanocidal activity of bergenin, the major constituent of Flueggea virosa, on Trypanosoma brucei.

B Nyasse1, J Nono, B Sonke, C Denier, C Fontaine.   

Abstract

The presence of bergenin in substantial amounts in the methanol leaves extract of Flueggea virosa (Euphorbiaceae) was established as a strong chemotaxomic point of differentiation between Flueggea virosa and Securinega virosa. Bergenin showed an inhibitory effect on the growth of the bloodstream form of Trypanosoma brucei with an IC50 value of 1 microM.

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Year:  2004        PMID： 15248469

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  5 in total

1.  Radical scavenging activity of selected medicinal plants from Limpopo province of South Africa.

Authors:  A M Chauke; L J Shai; P M Mphahlele; M A Mogale
Journal:  Afr J Tradit Complement Altern Med       Date:  2012-04-02

2.  Ethnodiagnostic skills of the digo community for malaria: a lead to traditional bioprospecting.

Authors:  Joseph Mwanzia Nguta; James M Mbaria; Peter K Gathumbi; Daniel Gakuya; John David Kabasa; Stephen Gitahi Kiama
Journal:  Front Pharmacol       Date:  2011-06-24       Impact factor: 5.810

3.  Evaluation of in vitro and in vivo antileishmanial potential of bergenin rich Bergenia ligulata (Wall.) Engl. root extract against visceral leishmaniasis in inbred BALB/c mice through immunomodulation.

Authors:  Rupinder Kaur; Sukhbir Kaur
Journal:  J Tradit Complement Med       Date:  2017-06-27

Review 4.  Antimalarial Plants Used across Kenyan Communities.

Authors:  Timothy Omara
Journal:  Evid Based Complement Alternat Med       Date:  2020-06-12       Impact factor: 2.629

5.  Development and validation of UPLC-PDA method for concurrent analysis of bergenin and menisdaurin in aerial parts of Flueggea virosa (Roxb. ex Willd.).

Authors:  Afzal Hussain; Perwez Alam; Nasir Ali Siddiqui; Mohamed Fahad Alajmi; Md Tabish Rehman; Mohd Abul Kalam; Adnan Jathlan Al-Rehaily
Journal:  Saudi Pharm J       Date:  2018-05-22       Impact factor: 4.330
  5 in total

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