Literature DB >> 15246899

Evaluation of a high-dose dexamethasone-eluting stent.

Rainer Hoffmann1, Roswitha Langenberg, Peter Radke, Andreas Franke, Rüdiger Blindt, Jan Ortlepp, Jeff J Popma, Christian Weber, Peter Hanrath.   

Abstract

This study evaluated the safety and efficacy of a dexamethasone-eluting stent with a special high dexamethasone-loading dose for treatment of de novo coronary lesions in 30 patients. Eight patients had in-stent restenosis (restenosis rate 31%) at 6-month follow-up, and the in-stent late lumen loss was 0.96 +/- 0.63 mm due to an average intimal hyperplasia area obstruction of 32 +/- 21%, indicating that high-dose dexamethasone-loaded stents do not significantly reduce neointimal proliferation.

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Year:  2004        PMID: 15246899     DOI: 10.1016/j.amjcard.2004.03.061

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  7 in total

1.  Hemocompatibility of Poly(vinyl alcohol)-Gelatin Core-Shell Electrospun Nanofibers: A Scaffold for Modulating Platelet Deposition and Activation.

Authors:  Valerie M Merkle; Daniel Martin; Marcus Hutchinson; Phat L Tran; Alana Behrens; Samir Hossainy; Jawaad Sheriff; Danny Bluestein; Xiaoyi Wu; Marvin J Slepian
Journal:  ACS Appl Mater Interfaces       Date:  2015-04-08       Impact factor: 9.229

2.  Steroid-eluting stents in patients with acute coronary syndrome: the dexamethasone eluting stent Italian registry.

Authors:  Flavio Ribichini; Fabrizio Tomai; Leonardo Paloscia; Germano Di Sciascio; Giuseppe Carosio; Michele Romano; Edoardo Verna; Mario Galli; Corrado Tamburino; Nicoletta De Cesare; Raimondo Pirisi; Federico Piscione; Giorgio Lanteri; Valeria Ferrero; Corrado Vassanelli
Journal:  Heart       Date:  2006-09-27       Impact factor: 5.994

Review 3.  Therapeutic manipulation of glucocorticoid metabolism in cardiovascular disease.

Authors:  Patrick W F Hadoke; Javaid Iqbal; Brian R Walker
Journal:  Br J Pharmacol       Date:  2009-02-23       Impact factor: 8.739

4.  Dexamethasone-loaded block copolymer nanoparticles induce leukemia cell death and enhance therapeutic efficacy: a novel application in pediatric nanomedicine.

Authors:  Vinu Krishnan; Xian Xu; Sonali P Barwe; Xiaowei Yang; Kirk Czymmek; Scott A Waldman; Robert W Mason; Xinqiao Jia; Ayyappan K Rajasekaran
Journal:  Mol Pharm       Date:  2012-11-29       Impact factor: 4.939

Review 5.  Glucocorticoids in the prevention of restenosis after coronary angioplasty: therapeutic potential.

Authors:  Valeria Ferrero; Flavio Ribichini; Gabriele Pesarini; Sandra Brunelleschi; Corrado Vassanelli
Journal:  Drugs       Date:  2007       Impact factor: 9.546

Review 6.  Modulation of 11β-hydroxysteroid dehydrogenase as a strategy to reduce vascular inflammation.

Authors:  Patrick W F Hadoke; Tiina Kipari; Jonathan R Seckl; Karen E Chapman
Journal:  Curr Atheroscler Rep       Date:  2013-05       Impact factor: 5.113

7.  Stent hypersensitivity and infection in sinus cavities.

Authors:  Nicholas G Kounis; George D Soufras; George Hahalis
Journal:  Allergy Rhinol (Providence)       Date:  2013
  7 in total

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