| Literature DB >> 15246461 |
Anja Basan1, Werner Kissling, Stefan Leucht.
Abstract
Randomized controlled trials comparing valproate (as a sole, or as an adjunctive compound) to placebo for patients with schizophrenia or schizophrenia-like disorders were summarized in a metaanalysis. It was possible to include only five trials (n = 379) examining valproate as add-on to antipsychotics in this review. Some of the single studies showed inconsistent beneficial effects on some aspects of response, but no overall superiority of valproate augmentation at study endpoints was shown.Entities:
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Year: 2004 PMID： 15246461 DOI： 10.1016/j.schres.2004.01.016
Source DB: PubMed Journal: Schizophr Res ISSN： 0920-9964 Impact factor: 4.939