BACKGROUND/AIMS: In industrialized countries hepatitis E virus (HEV) infection is rare and its diagnosis is difficult because the utility of available tests is not well established. METHODS: We studied the presence of acute HEV infection markers in a cluster of 11 cases of acute hepatitis with IgG anti-HEV antibodies. RESULTS: Three cases were confirmed as acute hepatitis E and 8 as presumptive hepatitis E, two as a past HEV infection and one could not be determined. Three different HEV strains were identified in serum from 3 patients. Two strains belonged to genotype 3, the predominant genotype found in local urban sewage and the other strain belonged to genotype 1 and was considered an imported strain. CONCLUSIONS: Our findings demonstrate the presence of some autochthonous, sporadic acute hepatitis E cases as well as an imported case in our area and the transitory nature of virological and serological markers for HEV.
BACKGROUND/AIMS: In industrialized countries hepatitis E virus (HEV) infection is rare and its diagnosis is difficult because the utility of available tests is not well established. METHODS: We studied the presence of acute HEV infection markers in a cluster of 11 cases of acute hepatitis with IgG anti-HEV antibodies. RESULTS: Three cases were confirmed as acute hepatitis E and 8 as presumptive hepatitis E, two as a past HEVinfection and one could not be determined. Three different HEV strains were identified in serum from 3 patients. Two strains belonged to genotype 3, the predominant genotype found in local urban sewage and the other strain belonged to genotype 1 and was considered an imported strain. CONCLUSIONS: Our findings demonstrate the presence of some autochthonous, sporadic acute hepatitis E cases as well as an imported case in our area and the transitory nature of virological and serological markers for HEV.
Authors: Maria Buti; Pere Plans; Angela Domínguez; Rossend Jardi; Francisco Rodriguez Frias; Rafael Esteban; Luis Salleras; Antoni Plasencia Journal: Clin Vaccine Immunol Date: 2008-03-05
Authors: Maria Buti; Angela Domínguez; Pere Plans; Rossend Jardí; Mélani Schaper; Jordi Espuñes; Neus Cardeñosa; Francisco Rodríguez-Frías; Rafael Esteban; Antoni Plasència; Luis Salleras Journal: Clin Vaccine Immunol Date: 2006-10-18
Authors: M Bouwknegt; B Engel; M M P T Herremans; M A Widdowson; H C Worm; M P G Koopmans; K Frankena; A M de Roda Husman; M C M De Jong; W H M Van Der Poel Journal: Epidemiol Infect Date: 2007-06-20 Impact factor: 2.451
Authors: Salceda Fernández-Barredo; Carolina Galiana; Angel García; Maria Teresa Gómez-Muñoz; Santiago Vega; Manuel A Rodríguez-Iglesias; Maria Teresa Pérez-Gracia Journal: Can J Vet Res Date: 2007-07 Impact factor: 1.310