Literature DB >> 15245864

In vitro activity of protegrin-1 and beta-defensin-1, alone and in combination with isoniazid, against Mycobacterium tuberculosis.

Lanfranco Fattorini1, Renato Gennaro, Margherita Zanetti, Dejiang Tan, Lara Brunori, Federico Giannoni, Manuela Pardini, Graziella Orefici.   

Abstract

The antimicrobial peptide protegrin-1 (PG-1) inhibited the growth in vitro of drug-susceptible and multidrug-resistant Mycobacterium tuberculosis; a lower activity was shown by human beta-defensin-1 (HBD-1) against both strains. The combination of PG-1 or HBD-1 with isoniazid significantly reduced M. tuberculosis growth in comparison with the peptides or isoniazid alone.

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Year:  2004        PMID： 15245864     DOI： 10.1016/j.peptides.2004.04.003

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  14 in total

Review 1.  Host defense peptides in the oral cavity and the lung: similarities and differences.

Authors:  G Diamond; N Beckloff; L K Ryan
Journal:  J Dent Res       Date:  2008-10       Impact factor: 6.116

2.  Induction of β-defensins by l-isoleucine as novel immunotherapy in experimental murine tuberculosis.

Authors:  C E Rivas-Santiago; B Rivas-Santiago; D A León; J Castañeda-Delgado; R Hernández Pando
Journal:  Clin Exp Immunol       Date:  2011-01-14       Impact factor: 4.330

3.  Kinetics and cellular sources of cathelicidin during the course of experimental latent tuberculous infection and progressive pulmonary tuberculosis.

Authors:  J Castañeda-Delgado; R Hernández-Pando; C J Serrano; D Aguilar-León; J León-Contreras; C Rivas-Santiago; R Méndez; I González-Curiel; A Enciso-Moreno; B Rivas-Santiago
Journal:  Clin Exp Immunol       Date:  2010-09       Impact factor: 4.330

4.  Enhanced resistance to bacterial infection in protegrin-1 transgenic mice.

Authors:  Queenie C K Cheung; Patricia V Turner; Cheng Song; De Wu; Hugh Y Cai; Janet I MacInnes; Julang Li
Journal:  Antimicrob Agents Chemother       Date:  2008-03-03       Impact factor: 5.191

5.  Anti-mycobacterial activity evaluation of designed peptides: cryptic and database filtering based approach.

Authors:  Sneha Raj; Umamageswaran Venugopal; Garima Pant; Mitra Kalyan; Jesu Arockiaraj; Manju Y Krishnan; Mukesh Pasupuleti
Journal:  Arch Microbiol       Date:  2021-07-09       Impact factor: 2.552

6.  Structure-Dependent Immune Modulatory Activity of Protegrin-1 Analogs.

Authors:  Susu M Zughaier; Pavel Svoboda; Jan Pohl
Journal:  Antibiotics (Basel)       Date:  2014-12

Review 7.  Defensins: The Case for Their Use against Mycobacterial Infections.

Authors:  Haodi Dong; Yue Lv; Deming Zhao; Paul Barrow; Xiangmei Zhou
Journal:  J Immunol Res       Date:  2016-09-20       Impact factor: 4.818

Review 8.  Host Antimicrobial Peptides: The Promise of New Treatment Strategies against Tuberculosis.

Authors:  Javier Arranz-Trullén; Lu Lu; David Pulido; Sanjib Bhakta; Ester Boix
Journal:  Front Immunol       Date:  2017-11-07       Impact factor: 7.561

Review 9.  The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions.

Authors:  Bee Ha Gan; Josephine Gaynord; Sam M Rowe; Tomas Deingruber; David R Spring
Journal:  Chem Soc Rev       Date:  2021-07-05       Impact factor: 54.564

10.  Short, Synthetic Cationic Peptides Have Antibacterial Activity against Mycobacterium smegmatis by Forming Pores in Membrane and Synergizing with Antibiotics.

Authors:  Kajal Gupta; Sameer Singh; Monique L van Hoek
Journal:  Antibiotics (Basel)       Date:  2015-08-24
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