Literature DB >> 15243661

[Tuberculosis contact tracing among children and adolescents, Brazil].

Zelina M R Caldeira1, Clemax C Sant'Anna, Miguel Abdom Aidé.   

Abstract

OBJECTIVE: To detect tuberculosis (TB) disease or infection among contacts of pulmonary TB patients.
METHODS: Cross-sectional study in a Primary Healthcare unit in Rio de Janeiro (Brazil) with 184 child and adolescent contacts of pulmonary TB patients between March 1995 and March 1997. Subjects underwent clinical evaluation, chest radiographs, and tuberculin skin tests (TST); sputum smears were performed whenever possible. TB cases found were submitted to treatment and infected patients to chemoprophylaxis. Tuberculin converters, who tested positive for TST eight weeks after an initial negative result, received chemoprophylaxis.
RESULTS: The sample included 98 boys and 86 girls; age ranged from 0 to 15 years; 26.9% were malnourished according to the Gomez criteria. Concerning the source of infection, 170 cases (92.4%) had household contacts, of which 66.5% were the child's parents. BCG vaccination was verified in 98.4% of children, and 14.7% of children had been revaccinated. Strong TST reactions were observed in 110/181 children. Seventy-six children (41.3%) were considered as infected by M. tuberculosis and 25 cases (13.6%) of TB were detected, of which seven (28%) were asymptomatic. There was greater occurrence of disease when the contact lived with more than one source of infection (p=0.02).
CONCLUSIONS: The detection of TB disease and infection was high in the studied population. Contact control must be emphasized, for it allows for the diagnosis of TB in children who are still asymptomatic, in addition to identifying infected subjects who may profit from chemoprophylaxis.

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Year:  2004        PMID: 15243661     DOI: 10.1590/s0034-89102004000300001

Source DB:  PubMed          Journal:  Rev Saude Publica        ISSN: 0034-8910            Impact factor:   2.106


  3 in total

1.  House-hold contact tuberculosis screening adherence and associated factors among tuberculosis patients attending at health facilities in Gondar town, northwest, Ethiopia.

Authors:  Dessie Alemnew Shiferaw; Habtamu Sewunet Mekonnen; Addisu Taye Abate
Journal:  BMC Infect Dis       Date:  2019-12-18       Impact factor: 3.090

2.  Latent Tuberculosis Infection Diagnostic and Treatment Cascade among Contacts in Primary Health Care in a City of Sao Paulo State, Brazil: Cross-Sectional Study.

Authors:  Anneliese Domingues Wysocki; Tereza Cristina Scatena Villa; Tiemi Arakawa; Maria Eugênia Firmino Brunello; Silvia Helena Figueiredo Vendramini; Aline Aparecida Monroe; Afranio Lineu Kritski
Journal:  PLoS One       Date:  2016-06-10       Impact factor: 3.240

3.  Tuberculosis contact tracing among children and adolescent referred to children's hospital in Rio de Janeiro, Brazil.

Authors:  Angela Marcia Cabral Mendonça; Afrânio Lineu Kritski; Clemax Couto Sant'Anna
Journal:  Braz J Infect Dis       Date:  2015-01-27       Impact factor: 3.257

  3 in total

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