Literature DB >> 15243565

Adenotonsillectomy for obstructive sleep apnea in obese children.

Ron B Mitchell1, James Kelly.   

Abstract

OBJECTIVE: To study changes in sleep behavior and quality of life in obese children after adenotonsillectomy for obstructive sleep apnea. Study design and setting Prospective study at the University of New Mexico Children's Hospital.
METHODS: Children who met inclusion criteria and had a respiratory distress index (RDI) greater than 5 were enrolled in the study and underwent adenotonsillectomy. All children underwent preoperative and postoperative full-night polysomnography. Age- and gender-specific percentile BMI was recorded at the time of polysomnography. Caregivers were asked to complete an OSA-18 quality of life survey prior to polysomnography and a second survey within 6 months of surgery. Scores from preoperative and postoperative polysomnography and OSA-18 surveys were compared using the paired Student's t test.
RESULTS: The study population included 30 children. Twenty-six children (86%) were male. The mean age of the children at the time of inclusion in the study was 9.3 years; range, 3.0 to 17.2. The mean preoperative BMI was 28.6 (range, 19.2 to 47.1) and the mean postoperative BMI was 27.9 (range, 17.8 to 27.9). A 2-tailed paired t test showed that this difference is not statistically significant (P = 0.06). The mean preoperative RDI was 30.0 and the mean postoperative RDI was 11.6 (P < 0.001). The preoperative mean total OSA-18 score was 78.2 and the postoperative mean total score was 39.8 (P < 0.001).
CONCLUSION: Obese children with OSA who undergo adenotonsillectomy show a marked improvement in RDI and in quality of life with no change in BMI. However, in the majority of children, OSA does not resolve.

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Year:  2004        PMID: 15243565     DOI: 10.1016/j.otohns.2004.02.024

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  28 in total

1.  The Childhood Adenotonsillectomy Trial (CHAT): rationale, design, and challenges of a randomized controlled trial evaluating a standard surgical procedure in a pediatric population.

Authors:  Susan Redline; Raouf Amin; Dean Beebe; Ronald D Chervin; Susan L Garetz; Bruno Giordani; Carole L Marcus; Renee H Moore; Carol L Rosen; Raanan Arens; David Gozal; Eliot S Katz; Ronald B Mitchell; Hiren Muzumdar; H G Taylor; Nina Thomas; Susan Ellenberg
Journal:  Sleep       Date:  2011-11-01       Impact factor: 5.849

2.  Characteristics and surgical and clinical outcomes of severely obese children with obstructive sleep apnea.

Authors:  Gulnur Com; John L Carroll; Xinyu Tang; Maria S Melguizo; Charles Bower; Supriya Jambhekar
Journal:  J Clin Sleep Med       Date:  2015-04-15       Impact factor: 4.062

3.  Natural history and management of pediatric obstructive sleep apnea—emerging concepts.

Authors:  Hari Bandla; Lynn A D'Andrea
Journal:  Sleep       Date:  2015-01-01       Impact factor: 5.849

4.  Relationship between sleep apnea, fat distribution, and insulin resistance in obese children.

Authors:  Craig A Canapari; Alison G Hoppin; T Bernard Kinane; Bijoy J Thomas; Martin Torriani; Eliot S Katz
Journal:  J Clin Sleep Med       Date:  2011-06-15       Impact factor: 4.062

5.  Anterior nasal resistance in obese children with obstructive sleep apnea syndrome.

Authors:  Sanghun Sin; David M Wootton; Joseph M McDonough; Kiran Nandalike; Raanan Arens
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Review 6.  Executive summary of respiratory indications for polysomnography in children: an evidence-based review.

Authors:  Merrill S Wise; Cynthia D Nichols; Madeleine M Grigg-Damberger; Carole L Marcus; Manisha B Witmans; Valerie G Kirk; Lynn A D'Andrea; Timothy F Hoban
Journal:  Sleep       Date:  2011-03-01       Impact factor: 5.849

7.  Application of desaturation index in post-surgery follow-up in children with obstructive sleep apnea syndrome.

Authors:  Jui-Fang Liu; Chih-Min Tsai; Mao-Chang Su; Meng-Chih Lin; Hsin-Ching Lin; Wei-Ju Lee; Kai-Sheng Hsieh; Chen-Kuang Niu; Hong-Ren Yu
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-08-17       Impact factor: 2.503

Review 8.  Physiological effects of obstructive sleep apnea syndrome in childhood.

Authors:  Hiren Muzumdar; Raanan Arens
Journal:  Respir Physiol Neurobiol       Date:  2013-05-23       Impact factor: 1.931

Review 9.  Childhood obesity and obstructive sleep apnea syndrome.

Authors:  Raanan Arens; Hiren Muzumdar
Journal:  J Appl Physiol (1985)       Date:  2009-10-29

10.  A randomized trial of adenotonsillectomy for childhood sleep apnea.

Authors:  Carole L Marcus; Reneé H Moore; Carol L Rosen; Bruno Giordani; Susan L Garetz; H Gerry Taylor; Ron B Mitchell; Raouf Amin; Eliot S Katz; Raanan Arens; Shalini Paruthi; Hiren Muzumdar; David Gozal; Nina Hattiangadi Thomas; Janice Ware; Dean Beebe; Karen Snyder; Lisa Elden; Robert C Sprecher; Paul Willging; Dwight Jones; John P Bent; Timothy Hoban; Ronald D Chervin; Susan S Ellenberg; Susan Redline
Journal:  N Engl J Med       Date:  2013-05-21       Impact factor: 91.245

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