Literature DB >> 15243111

Diagnostic utility and clinical significance of naso- and oropharyngeal samples used in a PCR assay to diagnose Mycoplasma pneumoniae infection in children with community-acquired pneumonia.

Ian C Michelow1, Kurt Olsen, Juanita Lozano, Lynn B Duffy, George H McCracken, R Doug Hardy.   

Abstract

PCR assays of naso- and oropharyngeal samples among hospitalized children appear equally effective for the diagnosis of serologically confirmed community-acquired mycoplasmal pneumonia. However, the combination of results from both sites yields optimal sensitivity (57%), specificity (98%), and positive (92%) and negative (82%) predictive values when compared with Mycoplasma pneumoniae enzyme-linked immunosorbent assay.

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Year:  2004        PMID: 15243111      PMCID: PMC446324          DOI: 10.1128/JCM.42.7.3339-3341.2004

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  11 in total

1.  Demonstration by a nested PCR for Mycoplasma pneumoniae that M. pneumoniae load in the throat is higher in patients hospitalised for M. pneumoniae infection than in non-hospitalised subjects.

Authors:  J Wendelien Dorigo-Zetsma; Sebastian A J Zaat; Aldwin J M Vriesema; Jacob Dankert
Journal:  J Med Microbiol       Date:  1999-12       Impact factor: 2.472

2.  Comparison of nasopharyngeal and throat swabs for the detection of Chlamydia pneumoniae and Mycoplasma pneumoniae by polymerase chain reaction.

Authors:  J Gnarpe; A Lundbäck; H Gnarpe; B Sundelöf
Journal:  Scand J Infect Dis Suppl       Date:  1997

3.  Rapid detection of Mycoplasma pneumoniae in clinical samples by real-time PCR.

Authors:  D Hardegger; D Nadal; W Bossart; M Altwegg; F Dutly
Journal:  J Microbiol Methods       Date:  2000-06       Impact factor: 2.363

4.  Comparison of nasopharyngeal aspirates and throat swab specimens in a polymerase chain reaction-based test for Mycoplasma pneumoniae.

Authors:  M Reznikov; T K Blackmore; J J Finlay-Jones; D L Gordon
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1995-01       Impact factor: 3.267

5.  Diagnosis of Streptococcus pneumoniae lower respiratory infection in hospitalized children by culture, polymerase chain reaction, serological testing, and urinary antigen detection.

Authors:  Ian C Michelow; Juanita Lozano; Kurt Olsen; Collin Goto; Nancy K Rollins; Faryal Ghaffar; Violeta Rodriguez-Cerrato; Maija Leinonen; George H McCracken
Journal:  Clin Infect Dis       Date:  2001-11-27       Impact factor: 9.079

Review 6.  Respiratory tract infections by Mycoplasma pneumoniae in children: a review of diagnostic and therapeutic measures.

Authors:  A Ferwerda; H A Moll; R de Groot
Journal:  Eur J Pediatr       Date:  2001-08       Impact factor: 3.183

7.  Laboratory diagnosis of Mycoplasma pneumoniae infection. 4. Antigen capture and PCR-gene amplification for detection of the Mycoplasma: problems of clinical correlation.

Authors:  J Williamson; B P Marmion; D A Worswick; T W Kok; G Tannock; R Herd; R J Harris
Journal:  Epidemiol Infect       Date:  1992-12       Impact factor: 2.451

8.  Comparison of PCR, culture, and serological tests for diagnosis of Mycoplasma pneumoniae respiratory tract infection in children.

Authors:  J W Dorigo-Zetsma; S A Zaat; P M Wertheim-van Dillen; L Spanjaard; J Rijntjes; G van Waveren; J S Jensen; A F Angulo; J Dankert
Journal:  J Clin Microbiol       Date:  1999-01       Impact factor: 5.948

9.  Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children.

Authors:  Ian C Michelow; Kurt Olsen; Juanita Lozano; Nancy K Rollins; Lynn B Duffy; Thedi Ziegler; Jaana Kauppila; Maija Leinonen; George H McCracken
Journal:  Pediatrics       Date:  2004-04       Impact factor: 7.124

10.  Diagnosis of Mycoplasma pneumoniae pneumonia in children.

Authors:  M E Waris; P Toikka; T Saarinen; S Nikkari; O Meurman; R Vainionpää; J Mertsola; O Ruuskanen
Journal:  J Clin Microbiol       Date:  1998-11       Impact factor: 5.948

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  17 in total

1.  Comparison of PCR for sputum samples obtained by induced cough and serological tests for diagnosis of Mycoplasma pneumoniae infection in children.

Authors:  Tsutomu Yamazaki; Mitsuo Narita; Nozomu Sasaki; Tsuyoshi Kenri; Yoshichika Arakawa; Tsuguo Sasaki
Journal:  Clin Vaccine Immunol       Date:  2006-06

2.  Comparison of Medical Subject Headings and standard terminology regarding performance of diagnostic tests.

Authors:  Philippe Michel; Evelyne Mouillet; L Rachid Salmi
Journal:  J Med Libr Assoc       Date:  2006-04

Review 3.  Optimal sampling sites and methods for detection of pathogens possibly causing community-acquired lower respiratory tract infections.

Authors:  K Loens; L Van Heirstraeten; S Malhotra-Kumar; H Goossens; M Ieven
Journal:  J Clin Microbiol       Date:  2008-11-19       Impact factor: 5.948

4.  Isothermal Detection of Mycoplasma pneumoniae Directly from Respiratory Clinical Specimens.

Authors:  Brianna L Petrone; Bernard J Wolff; Alexandra A DeLaney; Maureen H Diaz; Jonas M Winchell
Journal:  J Clin Microbiol       Date:  2015-07-15       Impact factor: 5.948

Review 5.  Molecular methods for the detection of Mycoplasma and ureaplasma infections in humans: a paper from the 2011 William Beaumont Hospital Symposium on molecular pathology.

Authors:  Ken B Waites; Li Xiao; Vanya Paralanov; Rose M Viscardi; John I Glass
Journal:  J Mol Diagn       Date:  2012-07-20       Impact factor: 5.568

6.  Mycoplasma pneumoniae Among Children Hospitalized With Community-acquired Pneumonia.

Authors:  Preeta K Kutty; Seema Jain; Thomas H Taylor; Anna M Bramley; Maureen H Diaz; Krow Ampofo; Sandra R Arnold; Derek J Williams; Kathryn M Edwards; Jonathan A McCullers; Andrew T Pavia; Jonas M Winchell; Stephanie J Schrag; Lauri A Hicks
Journal:  Clin Infect Dis       Date:  2019-01-01       Impact factor: 9.079

7.  Role of Serum Mycoplasma pneumoniae IgA, IgM, and IgG in the Diagnosis of Mycoplasma pneumoniae-Related Pneumonia in School-Age Children and Adolescents.

Authors:  Wei-Ju Lee; Eng-Yen Huang; Chih-Min Tsai; Kuang-Che Kuo; Yi-Chuan Huang; Kai-Sheng Hsieh; Chen-Kuang Niu; Hong-Ren Yu
Journal:  Clin Vaccine Immunol       Date:  2017-01-05

Review 8.  New insights into the pathogenesis and detection of Mycoplasma pneumoniae infections.

Authors:  Ken B Waites; Mitchell F Balish; T Prescott Atkinson
Journal:  Future Microbiol       Date:  2008-12       Impact factor: 3.165

9.  Mycoplasma pneumonia: Clinical features and management.

Authors:  Surender Kashyap; Malay Sarkar
Journal:  Lung India       Date:  2010-04

10.  The role of Mycoplasma in upper respiratory infections.

Authors:  Ken B Waites; T Prescott Atkinson
Journal:  Curr Infect Dis Rep       Date:  2009-05       Impact factor: 3.725

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