| Literature DB >> 15242717 |
Abstract
Drug hypersensitivity reactions can lead to a great variety of different diseases. The main cause is a specific interaction of antibodies or T cells with a drug. In addition to the hapten concept, some drugs can bind directly to T-cell receptors and stimulate them. Based on recent investigation on different exanthemas, an extended classification of the Gell and Coombs type IV reaction is proposed.Entities:
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Year: 2004 PMID： 15242717 DOI： 10.1016/j.iac.2004.03.012
Source DB: PubMed Journal: Immunol Allergy Clin North Am ISSN： 0889-8561 Impact factor: 3.479