Literature DB >> 15242492

Heterotopic gastric mucosa in the cervical esophagus (inlet patch): endoscopic prevalence, histological and clinical characteristics.

Nihat Akbayir1, Canan Alkim, Levent Erdem, H Mehmet Sökmen, Ayşim Sungun, Tülay Başak, Suat Turgut, Zeynel Mungan.   

Abstract

BACKGROUND AND AIM: Heterotopic gastric mucosal patch, which has a 0.1-10% frequency, is encountered when the cervical esophagus is examined carefully during endoscopy. In this study, we aimed to determine the prevalence of the patch in the cervical esophagus, to identify its macroscopic and histological characteristics and to evaluate demographic and clinical features.
METHODS: Six hundred and sixty patients (317 male, 343 female; mean age 50.28 years, range 14-90) with upper gastrointestinal symptoms had elective esophagogastroduodenoscopy and the cervical esophagus was examined for the patch during withdrawal of the endoscope. Biopsies were obtained from the antrum and the patch. Helicobacter pylori was assessed using an immunohistochemical method.
RESULTS: The patch was found in 11 patients of 660, with a prevalence of 1.67%. Patch size ranged between 5 and 30 mm, appeared as a single patch in nine patients and as twin patches in two patients. Mean age and male : female ratio were not significantly different from the patient population without patches, but the female sex was predominant (three men, eight women; mean age 43.6 years, range 32-64). In five of 11 patients, the upper esophageal and laryngopharyngeal symptoms were remarkable. Eight patients in whom histological confirmation was carried out showed three fundic and five antral-type mucosa. Two of five patients with antral H. pylori also had the bacteria in the patch. H. pylori prevalence in the patch was 25%.
CONCLUSION: Heterotopic gastric mucosal patches in the proximal esophagus should not be overlooked during endoscopy because they may lead to important complications in relation to their acid secretion, which may vary according to their parietal cell mass.

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Year:  2004        PMID: 15242492     DOI: 10.1111/j.1440-1746.2004.03474.x

Source DB:  PubMed          Journal:  J Gastroenterol Hepatol        ISSN: 0815-9319            Impact factor:   4.029


  20 in total

1.  Heterotopic gastric mucosal patch of the esophagus is associated with higher prevalence of laryngopharyngeal reflux symptoms.

Authors:  Vui Heng Chong; Anand Jalihal
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-05-01       Impact factor: 2.503

2.  Awareness of the endoscopist affects detection rate of heterotopic gastric mucosa in esophagus.

Authors:  E Korkut; M Bektas; B Savas; F Memmedzade; E Oztas; Y Ustün; R Idilman; A Ozdena
Journal:  Indian J Gastroenterol       Date:  2009 Mar-Apr

Review 3.  Cervical inlet patch: new insights into diagnosis and endoscopic therapy.

Authors:  Radu Rusu; Sauid Ishaq; Terry Wong; Jason M Dunn
Journal:  Frontline Gastroenterol       Date:  2017-11-09

4.  Symptomatic gastric inlet patches in children treated with argon plasma coagulation: a case series.

Authors:  John Brannon Alberty; Ricardo Chanis; Vikram Khoshoo
Journal:  J Interv Gastroenterol       Date:  2012-04-01

5.  Endoscopic diagnosis of cervical esophageal heterotopic gastric mucosa with conventional and narrow-band images.

Authors:  Chi-Liang Cheng; Cheng-Hui Lin; Nai-Jen Liu; Jui-Hsiang Tang; Yen-Lin Kuo; Yi-Ning Tsui
Journal:  World J Gastroenterol       Date:  2014-01-07       Impact factor: 5.742

6.  High oesophageal web formation in association with heterotopic gastric mucosa (the gastric inlet patch): a small case series.

Authors:  Eric J Ainley
Journal:  Frontline Gastroenterol       Date:  2011-01-12

7.  Cervical inlet patch-optical coherence tomography imaging and clinical significance.

Authors:  Chao Zhou; Tejas Kirtane; Tsung-Han Tsai; Hsiang-Chieh Lee; Desmond C Adler; Joseph M Schmitt; Qin Huang; James G Fujimoto; Hiroshi Mashimo
Journal:  World J Gastroenterol       Date:  2012-05-28       Impact factor: 5.742

8.  Prevalence, histologic and clinical characteristics of heterotopic gastric mucosa in Chinese patients.

Authors:  Yu Fang; Lei Chen; Dong-Feng Chen; Wan-Ying Ren; Cai-Fei Shen; Yin Xu; Yi-Ju Xia; Jing-Wen Li; Pu Wang; An-Ran Zhang; Shun-Zi Shao; Xiao-Na Yu; Gui-Yong Peng; Dian-Chun Fang
Journal:  World J Gastroenterol       Date:  2014-12-14       Impact factor: 5.742

Review 9.  Clinical significance of heterotopic gastric mucosal patch of the proximal esophagus.

Authors:  Vui Heng Chong
Journal:  World J Gastroenterol       Date:  2013-01-21       Impact factor: 5.742

10.  Adenocarcinoma of Cervical Esophagus Arising in the Barrett's Mucosa.

Authors:  Deepak Sundriyal; Nikhil Shirsi; Sumedha Kotwal; Sushil Kumar; K Mithran Parthasarthy; Mahesh Gupta
Journal:  Indian J Surg Oncol       Date:  2015-02-20
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