Literature DB >> 15242194

Surgical-site infection rates and risk factor analysis in coronary artery bypass graft surgery.

Glenys Harrington1, Philip Russo, Denis Spelman, Sue Borrell, Kerrie Watson, Wendy Barr, Rhea Martin, Diedre Edmonds, Joanne Cocks, John Greenbough, Jill Lowe, Leesa Randle, Jan Castell, Elizabeth Browne, Kaye Bellis, Melissa Aberline.   

Abstract

BACKGROUND: The Victorian Infection Control Surveillance Project (VICSP) is a multicenter collaborative surveillance project established by infection control practitioners. Five public hospitals contributed data for patients undergoing coronary artery bypass graft (CABG) surgery.
OBJECTIVE: To determine the aggregate and comparative interhospital surgical-site infection (SSI) rates for patients undergoing CABG surgery and the risk factors for SSI in this patient group.
METHOD: Each institution used standardized definitions of SSI, risk adjustment, and reporting methodology according to the National Nosocomial Infections Surveillance System of the Centers for Disease Control and Prevention. Data on potential risk factors were prospectively collected.
RESULTS: For 4,474 patients undergoing CABG surgery, the aggregate SSI rate was 7.8 infections per 100 procedures (95% confidence interval [CI95], 7.0-8.5), with individual institutions ranging between 4.5 and 10.7 infections per 100 procedures. Multivariate risk factor analysis demonstrated age (odds ratio [OR], 1.02; CI95, 1.01-1.04; P < .001), obesity (OR, 1.8; CI95, 1.4-2.3; P < .001), and diabetes mellitus (OR, 1.6; CI95, 1.2-2.1; P < .001) as independent predictors of SSI. Three hundred thirty-four organisms were isolated from 296 SSIs. Of the total SSIs, methicillin-resistant Staphylococcus aureus was isolated from 32%, methicillin-sensitive S. aureus from 24%, gram-negative bacilli (eg, Enterobacter and Escherichia coli) from 18%, and miscellaneous organisms from the remainder.
CONCLUSION: We documented aggregate and comparative SSI rates among five Victorian public hospitals performing CABG surgery and defined specific independent risk factors for SSI. VICSP data offer opportunities for targeted interventions to reduce SSI following cardiac surgery.

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Year:  2004        PMID: 15242194     DOI: 10.1086/502424

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  27 in total

1.  Preoperative cigarette smoking and short-term morbidity and mortality after cardiac surgery: a meta-analysis.

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2.  A new hydrocolloid dressing prevents surgical site infection of median sternotomy wounds.

Authors:  Hideki Teshima; Hiroshi Kawano; Hideyuki Kashikie; Katsuhiko Nakamura; Tatsuya Imada; Takeshi Oda; Shigeaki Aoyagi
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3.  Epidemiology and outcome of major postoperative infections following cardiac surgery: risk factors and impact of pathogen type.

Authors:  Luke F Chen; Jean Marie Arduino; Shubin Sheng; Lawrence H Muhlbaier; Zeina A Kanafani; Anthony D Harris; Thomas G Fraser; Keith Allen; G Ralph Corey; Vance G Fowler
Journal:  Am J Infect Control       Date:  2012-05-19       Impact factor: 2.918

4.  Surgical site infections after coronary artery bypass graft surgery: incidence, perioperative hospital stay, readmissions, and revision surgeries.

Authors:  M Cristofolini; D Worlitzsch; A Wienke; R-E Silber; M Borneff-Lipp
Journal:  Infection       Date:  2012-06-15       Impact factor: 3.553

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Authors:  Saeed A Alqahtani; Abdullah S Alsultan; Hussain M Alqattan; Ahmed Eldemerdash; Turki B Albacker
Journal:  Antimicrob Agents Chemother       Date:  2018-06-26       Impact factor: 5.191

6.  An Assessment Scale for Patients with Postoperative Superficial Incisional Surgical Site Infection: a Cross-Sectional Study.

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7.  Population Pharmacokinetic Model-Based Evaluation of Standard Dosing Regimens for Cefuroxime Used in Coronary Artery Bypass Graft Surgery with Cardiopulmonary Bypass.

Authors:  Saeed A Alqahtani; Abdullah S Alsultan; Hussain M Alqattan; Ahmed Eldemerdash; Turki B Albacker
Journal:  Antimicrob Agents Chemother       Date:  2018-03-27       Impact factor: 5.191

Review 8.  Preventing deep wound infection after coronary artery bypass grafting: a review.

Authors:  Charles S Bryan; William M Yarbrough
Journal:  Tex Heart Inst J       Date:  2013

Review 9.  Surgical site infections in older adults: epidemiology and management strategies.

Authors:  Michael H Young; Laraine Washer; Preeti N Malani
Journal:  Drugs Aging       Date:  2008       Impact factor: 3.923

10.  Laparoscopic ventral hernia repair (LVHR) in morbidly obese patients.

Authors:  Z Tsereteli; B A Pryor; B T Heniford; A Park; G Voeller; B J Ramshaw
Journal:  Hernia       Date:  2007-12-04       Impact factor: 4.739

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