Literature DB >> 15241647

Inhibitory effect of electroacupuncture (EA) on the pressor response induced by exercise stress.

Peng Li1, Olasimbo Ayannusi, Cheryl Reid, John C Longhurst.   

Abstract

We examined the effect of EA on the exercise stress-induced pressor response in healthy adult subjects of both sexes. Each subject was subjected to a bicycle exercise test using a ramp protocol once/week for three or four weeks. Subjects were asked to perform the following tests in random order: 1) a baseline exercise test without EA and 2) exercise after acupuncture at P 5-6, LI 4-L 7 and/or G 37-39 acupoints. Brachial systolic (SBP), diastolic (DBP), and mean blood pressures (MBP), heart rate (HR) and the rate-pressure product (RPP, systolic BP x HR/100) were measured every three min, while a 12 lead ECG was monitored continuously. We observed increases in MBP, SBP, HR and RPP in all 17 subjects during exercise. In 12 of the 17 subjects (71 %), EA for 30 min before exercise, either at Jianshi-Neiguan acupoints (P 5-6) or Hegu-Lique acupoints (LI 4-L 7), led to an increase in maximal workload, and reduced peak SBP, MBP and RPP responses to exercise; EA did not alter DBP or HR responses in these subjects. EA at control acupoints (Guangming-Xuanzhong acupoints, G 37-39) in five subjects did not alter the hemodynamic responses. Seven additional subjects were enrolled to study the effect of EA during a bicycle exercise test using a constant workload. The results were similar, in five of the seven subjects SBP, MBP and RPP after exercise were attenuated significantly by EA at P 5-6. We conclude that EA at specific acupoints improves exercise capacity and reduces the hemodynamic responses in approximately 70% of normal subjects.

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Year:  2004        PMID: 15241647     DOI: 10.1007/s10286-004-0175-1

Source DB:  PubMed          Journal:  Clin Auton Res        ISSN: 0959-9851            Impact factor:   4.435


  30 in total

1.  Nucleus ambiguus cholinergic neurons activated by acupuncture: relation to enkephalin.

Authors:  Zhi-Ling Guo; Min Li; John C Longhurst
Journal:  Brain Res       Date:  2012-01-12       Impact factor: 3.252

2.  Electroacupuncture modulation of reflex hypertension in rats: role of cholecystokinin octapeptide.

Authors:  Min Li; Stephanie C Tjen-A-Looi; Zhi-Ling Guo; John C Longhurst
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2013-06-19       Impact factor: 3.619

3.  The status and future of acupuncture mechanism research.

Authors:  Vitaly Napadow; Andrew Ahn; John Longhurst; Lixing Lao; Elisabet Stener-Victorin; Richard Harris; Helene M Langevin
Journal:  J Altern Complement Med       Date:  2008-09       Impact factor: 2.579

4.  Spinal nociceptin mediates electroacupuncture-related modulation of visceral sympathoexcitatory reflex responses in rats.

Authors:  Wei Zhou; Aman Mahajan; John C Longhurst
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-06-26       Impact factor: 4.733

5.  Neural mechanism of electroacupuncture's hypotensive effects.

Authors:  Peng Li; John C Longhurst
Journal:  Auton Neurosci       Date:  2010-05-05       Impact factor: 3.145

Review 6.  Acupuncture's Cardiovascular Actions: A Mechanistic Perspective.

Authors:  John Longhurst
Journal:  Med Acupunct       Date:  2013-04

7.  Modulation of cardiopulmonary depressor reflex in nucleus ambiguus by electroacupuncture: roles of opioids and γ-aminobutyric acid.

Authors:  Stephanie C Tjen-A-Looi; Peng Li; Min Li; John C Longhurst
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-12-28       Impact factor: 3.619

8.  Electroacupuncture enhances preproenkephalin mRNA expression in rostral ventrolateral medulla of rats.

Authors:  Min Li; Stephanie C Tjen-A-Looi; John C Longhurst
Journal:  Neurosci Lett       Date:  2010-04-24       Impact factor: 3.046

9.  Electroacupuncture most effectively elicits depressor and bradycardic responses at 1 Hz in humans.

Authors:  Hidehiro Nakahara; Toru Kawada; Shin-ya Ueda; Eriko Kawai; Hiromi Yamamoto; Masaru Sugimachi; Tadayoshi Miyamoto
Journal:  Clin Auton Res       Date:  2015-12-22       Impact factor: 4.435

10.  Repetitive electroacupuncture causes prolonged increased met-enkephalin expression in the rVLM of conscious rats.

Authors:  Min Li; Stephanie C Tjen-A-Looi; Zhi-Ling Guo; John C Longhurst
Journal:  Auton Neurosci       Date:  2012-07-26       Impact factor: 3.145

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