Literature DB >> 1524

[Adrenergic and cholinergic control of oxytocin release evoked by vaginal, vagal and mammary stimulation in lactating rats (author's transl)].

F Moos, P Richard.   

Abstract

1. The amounts of oxytocin released during Ferguson and vago-pituitary reflexes are estimated by measurements of intramammary pressure. For the milk-ejection reflex, the gain in weight of the young over a period of 30 minutes is taken as an indirect index of the release of oxytocin. 2. Antagonists of specific cholinoceptors and adrenoceptors were injected into the third ventricle in order to delineate the role of the mediators and receptors in the control of oxytocin release. 3. The results suggest that three reflexes have a specific chemical transmission since: a) The Ferguson reflex is inhibited by the drugs that only block alpha and beta adrenoceptors. b) The vago-pituitary reflex is inhibited by the drugs that block alpha and beta adrenoceptors and muscarinic cholinoceptors. c) The milk-ejection reflex is inhibited by the drugs that block alpha adrenoceptors and muscarinic and nicotinic cholinoceptors.

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Year:  1975        PMID: 1524

Source DB:  PubMed          Journal:  J Physiol (Paris)        ISSN: 0021-7948


  2 in total

1.  Reproducible increases in intramammary pressure after spinal cord stimulation in lactating rats.

Authors:  D A Poulain; R G Dyer
Journal:  Exp Brain Res       Date:  1984       Impact factor: 1.972

2.  Effects of cholinoceptor antagonists on the suckling-induced and experimentally evoked release of oxytocin.

Authors:  G Clarke; C H Fall; D W Lincoln; L P Merrick
Journal:  Br J Pharmacol       Date:  1978-07       Impact factor: 8.739

  2 in total

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