Literature DB >> 15239350

Evolution of dilated cardiomyopathy (DCM) from idiopathic hypertrophic cardiomyopathy (IHCM) vs. inflammatory dilated cardiomyopathy (DCMi): a rare case of sudden death in an 8-year-old boy.

Reinhard Dettmeyer1, Peter Schmidt, Reinhard Kandolf, Burkhard Madea.   

Abstract

In rare cases, the diagnosis of hypertrophic and dilated cardiomyopathy (DCM) in children was established postmortem. Our case report deals with the sudden and unexpected death of an 8-year-old boy. The postmortem examination revealed non-obstructive hypertrophy with irregular arrangement of muscular fibers, dilatation of the ventricles, endocardial fibrosis, microfocal vacuolization with enlarged hyperchromatic nuclei, and signs of inflammation with interstitial fibrosis. We present an evolution from idiopathic cardiomyopathy to DCM. To some extent, there were morphologic signs of an inflammatory process that first led us to suspect a specific inflammatory DCM.

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Year:  2004        PMID: 15239350     DOI: 10.1016/j.prp.2004.03.005

Source DB:  PubMed          Journal:  Pathol Res Pract        ISSN: 0344-0338            Impact factor:   3.250


  1 in total

1.  Global microRNA profiles and signaling pathways in the development of cardiac hypertrophy.

Authors:  H J Feng; W Ouyang; J H Liu; Y G Sun; R Hu; L H Huang; J L Xian; C F Jing; M J Zhou
Journal:  Braz J Med Biol Res       Date:  2014-05-02       Impact factor: 2.590

  1 in total

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