Literature DB >> 15238918

Airway eicosanoids in acute severe respiratory syncytial virus bronchiolitis.

Yves Sznajer1, Jay Y Westcott, Sally E Wenzel, Bruce Mazer, Marisa Tucci, Baruch Joseph Toledano.   

Abstract

We prospectively studied the levels of eicosanoids in intubated patients with severe bronchiolitis and compared them to electively intubated non-infected infants. LeukotrieneE(4) (LTE(4)), leukotrieneB(4) (LTB(4)), and prostaglandinE(2) (PGE(2)) levels were significantly increased (P <.01) from endotracheal (ET) aspirates of infants with bronchiolitis compared with controls, as were urinary LTE(4) levels (P <.001). We conclude that eicosanoids are increased in the tracheal aspirates and urine of children with bronchiolitis.

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Year:  2004        PMID： 15238918     DOI： 10.1016/j.jpeds.2004.03.049

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  15 in total

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