Literature DB >> 15237991

A diversity-oriented strategy for the construction of tetrasubstituted pyrroles via coupled domino processes.

David Tejedor1, David González-Cruz, Fernando García-Tellado, José Juan Marrero-Tellado, Matías López Rodríguez.   

Abstract

A new microwave-assisted rearrangement of 1,3-oxazolidines scaffolds is the basis for a new, metal-free, direct, and modular construction of tetrasubstituted pyrroles from terminal-conjugated alkynes, aldehydes, and primary amines. This new reaction manifold entails two linked domino processes in a one-pot manner with both atom- and bond-efficiency and under very simple and environment-friendly experimental conditions.

Entities:  

Year:  2004        PMID： 15237991     DOI： 10.1021/ja047396p

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  3 in total

1.  Revisit to the synthesis of 1,2,3,4-tetrasubstituted pyrrole derivatives in lactic acid media as a green solvent and catalyst.

Authors:  Dilek Akbaslar; E Sultan Giray; Oztekin Algul
Journal:  Mol Divers       Date:  2020-09-27       Impact factor: 2.943

2.  Metal-catalyzed 1,2-shift of diverse migrating groups in allenyl systems as a new paradigm toward densely functionalized heterocycles.

Authors:  Alexander S Dudnik; Anna W Sromek; Marina Rubina; Joseph T Kim; Alexander V Kel'in; Vladimir Gevorgyan
Journal:  J Am Chem Soc       Date:  2008-01-04       Impact factor: 15.419

3.  Ceria-Vanadia/Silica-Catalyzed Cascade for C-C and C-O Bond Activation: Green One-Pot Synthesis of 2-Amino-3-cyano-4H-pyrans.

Authors:  Surya Narayana Maddila; Suresh Maddila; Werner E van Zyl; Sreekantha B Jonnalagadda
Journal:  ChemistryOpen       Date:  2015-08-19       Impact factor: 2.911
  3 in total

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