Literature DB >> 15237770

Effectiveness of immunotherapy for recurring sinusitis associated with allergic rhinitis as assessed by the Sinusitis Outcomes Questionnaire.

Robert A Nathan1, John Santilli, William Rockwell, Jeffrey Glassheim.   

Abstract

BACKGROUND: Outcomes measurement is a proficient method for determining the effectiveness of medical therapy. Currently, there are no easy-to-use and inexpensive questionnaires available to evaluate the impact of immunotherapy in the treatment of sinusitis by allergists, given the research constraints of a private practice setting.
OBJECTIVE: To measure the effectiveness of immunotherapy in the overall treatment of atopic patients with associated sinusitis in a private practice setting.
METHODS: A total of 114 patients with a history of rhinitis and sinusitis and positive radiographic evidence of sinus disease were consecutively chosen from 3 private practices nationwide and surveyed for global symptoms and specific symptoms related to the nose, sinuses, eyes, and chest with the Sinusitis Outcomes Questionnaire (SOQ). Their medical history, including prior treatment, was evaluated. This questionnaire was administered twice in one sitting, with the first a recall of symptoms before starting immunotherapy and the second an evaluation of current symptoms.
RESULTS: The data revealed that 99% believed immunotherapy worked, with 1% unsure. Patients experienced a 72% decrease in days lost from work or school and a 26% reduction in the use of medications per year. There was a mean reduction of 51% in the overall symptom score of the patients after receiving immunotherapy.
CONCLUSIONS: This study demonstrates that the user-friendly SOQ can be effectively and inexpensively used in a private practice setting and suggests that immunotherapy is an effective treatment for patients with sinus disease and allergic rhinitis.

Entities:  

Mesh:

Year:  2004        PMID: 15237770     DOI: 10.1016/S1081-1206(10)61435-4

Source DB:  PubMed          Journal:  Ann Allergy Asthma Immunol        ISSN: 1081-1206            Impact factor:   6.347


  9 in total

1.  Diagnostic tools in Rhinology EAACI position paper.

Authors:  Glenis Scadding; Peter Hellings; Isam Alobid; Claus Bachert; Wytske Fokkens; Roy Gerth van Wijk; Philippe Gevaert; Josep Guilemany; Livije Kalogjera; Valerie Lund; Joaquim Mullol; Giovanni Passalacqua; Elina Toskala; Cornelius van Drunen
Journal:  Clin Transl Allergy       Date:  2011-06-10       Impact factor: 5.871

Review 2.  [Immunotherapy with allergen extracts for allergic rhinitis].

Authors:  H Riechelmann
Journal:  HNO       Date:  2005-06       Impact factor: 1.284

Review 3.  Chronic rhinosinusitis phenotypes.

Authors:  John W Steinke; Larry Borish
Journal:  Ann Allergy Asthma Immunol       Date:  2016-09       Impact factor: 6.347

Review 4.  The Role of Allergen-Specific Immunotherapy in ENT Diseases: A Systematic Review.

Authors:  Elena Cantone; Stefania Gallo; Sara Torretta; Aikaterini Detoraki; Carlo Cavaliere; Claudio Di Nola; Luca Spirito; Tiziana Di Cesare; Stefano Settimi; Daniela Furno; Lorenzo Pignataro; Eugenio De Corso
Journal:  J Pers Med       Date:  2022-06-09

Review 5.  Chronic sinusitis pathophysiology: the role of allergy.

Authors:  Joshua L Kennedy; Larry Borish
Journal:  Am J Rhinol Allergy       Date:  2013-04-18       Impact factor: 2.467

Review 6.  The impact of allergic and nonallergic rhinitis on pediatric sinusitis.

Authors:  Brian A Smart
Journal:  Curr Allergy Asthma Rep       Date:  2006-05       Impact factor: 4.919

7.  The role of house dust mite immunotherapy in Indonesian children with chronic rhinosinusitis allergy: A randomized control trial.

Authors:  Azwin Mengindra Putera; Zahrah Hikmah; Anang Endaryanto; Margarita Maria Maramis
Journal:  Heliyon       Date:  2021-03-16

Review 8.  Allergic Rhinitis: What Do We Know About Allergen-Specific Immunotherapy?

Authors:  Tadech Boonpiyathad; Mongkol Lao-Araya; Chirawat Chiewchalermsri; Sasipa Sangkanjanavanich; Hideaki Morita
Journal:  Front Allergy       Date:  2021-10-28

9.  Clinical Evidence and Biomarkers Linking Allergy and Acute or Chronic Rhinosinusitis in Children: a Systematic Review.

Authors:  Eugenio De Corso; Daniela Lucidi; Elena Cantone; Giancarlo Ottaviano; Tiziana Di Cesare; Veronica Seccia; Gaetano Paludetti; Jacopo Galli
Journal:  Curr Allergy Asthma Rep       Date:  2020-09-05       Impact factor: 4.806

  9 in total

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