Successful pregnancy after vaginal cancer treated with interferon.

A 25-year-old white woman with a vaginal invasive epidermal carcinoma was treated with interferon-alpha 2b (3,000,000 U intralesional, every two days for a total of 18 applications). Follow-up with Papanicolaou and colposcopy showed complete regression of the vaginal lesion, After three years the patient got pregnant. The prenatal course was uneventful and a vaginal delivery was performed. She is currently in follow-up without any signs of recurrence.