| Literature DB >> 15237302 |
M Konno1, T Kirikae, K Suzuki, M Yoshida, K J Mori, R Wakusawa.
Abstract
The effects of prolonged exposure to nitrous oxide on the hemopoietic progenitor cells in bone marrow and spleen in mice were investigated. Fifty percent nitrous oxide caused a marked decrease in the number of pluripotent stem cells (CFU-S) and granulocyte-macro-phage progenitor cells (GM-CFC) in the spleen, whereas it caused only a slight decrease in these cells in the bone marrow. These results suggest that prolonged exposure to nitrous oxide induces damage in the splenic hemopoiesis in mice.Entities:
Year: 1987 PMID: 15237302 DOI: 10.1007/s0054070010029
Source DB: PubMed Journal: J Anesth ISSN: 0913-8668 Impact factor: 2.078