Literature DB >> 15236839

QSAR study on carbonic anhydrase inhibitors: aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties, with topical activity as antiglaucoma agents.

Vijay K Agrawal1, Shahnaz Bano, Claudiu T Supuran, Padmakar V Khadikar.   

Abstract

Quantitative structure-activity-relationship (QSAR) study on aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl carbonic anhydrase (CA) inhibitors has been carried out topologically using first-order valence connectivity index ((1)chi(v)). Excellent results are obtained against all the three isozymes; CA I, II and IV of the zinc enzyme CA by using indicator parameters along with (1)chi(v).

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Year:  2004        PMID： 15236839     DOI： 10.1016/j.ejmech.2004.03.002

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  3 in total

1.  Thiacalix[4]arene-tetra-(quinoline-8- sulfonate): a Sensitive and Selective Fluorescent Sensor for Co (II).

Authors:  Krunal Modi; Urvi Panchal; Shuvankar Dey; Chirag Patel; Anita Kongor; Himanshu A Pandya; V K Jain
Journal:  J Fluoresc       Date:  2016-07-09       Impact factor: 2.217

2.  Competitive inhibitory effects of acetazolamide upon interactions with bovine carbonic anhydrase II.

Authors:  Shahrokh Safarian; Fatemeh Bagheri; Ali Akbar Moosavi-Movahedi; Massoud Amanlou; Nader Sheibani
Journal:  Protein J       Date:  2007-09       Impact factor: 2.371

3.  Some QSAR studies for a group of sulfonamide Schiff base as carbonic anhydrase CA II inhibitors.

Authors:  Erol Eroglu
Journal:  Int J Mol Sci       Date:  2008-02-26       Impact factor: 6.208
  3 in total

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