Literature DB >> 15236041

Effects of intravenously administered human atrial natriuretic peptide on elevated blood pressure during surgery.

N Iwatsuki1, M Katoh, A Yasuda, S Saitoh, M Asano.   

Abstract

The effect of human atrial natriuretic peptide (hANP) on blood pressure (Bp) was evaluated in 11 patients who had elevated systoric Bp of over 150 mmHg during surgery. A bolus injection of 50 microg or 100 microg of hANP decreased Bp with an immediate response by 27.6 +/- 3.1 mmHg (P < 0.001) or 40.7 +/- 4.2 mmHg (P < 0.001), respectively, accompanying with tremendously increased urine output. Heart rate and PaO2 were not altered. Thus, a intravenous bolus injection of hANP is an useful therapeutic tool for the treatment of acutely elevated Bp during anesthesia.

Entities:  

Year:  1989        PMID： 15236041     DOI： 10.1007/s0054090030218

Source DB:  PubMed          Journal:  J Anesth        ISSN： 0913-8668            Impact factor:   2.078


  12 in total

1.  Effects of atrial natriuretic peptide on systemic haemodynamics and cardiac function in normal man.

Authors:  M J Allen; S M Gilmour; M Singer; E D Bennett
Journal:  Cardiovasc Res       Date:  1989-01       Impact factor: 10.787

2.  Arterial hypoxemia following the administration of sublingual nitroglycerin.

Authors:  E A Kopman; G R Weygandt; S Bauer; T B Ferguson
Journal:  Am Heart J       Date:  1978-10       Impact factor: 4.749

Review 3.  Atrial natriuretic hormone, the renin-aldosterone axis, and blood pressure-electrolyte homeostasis.

Authors:  J H Laragh
Journal:  N Engl J Med       Date:  1985-11-21       Impact factor: 91.245

4.  The effects of human atrial 28-amino acid peptide on systemic and renal hemodynamics in anesthetized rats.

Authors:  Y Hirata; M Ishii; T Sugimoto; H Matsuoka; T Sugimoto; K Kangawa; H Matsuo
Journal:  Circ Res       Date:  1985-10       Impact factor: 17.367

5.  Cardiovascular effects of intravenous and intracoronary administration of atrial natriuretic peptide in halothane anesthetized dogs.

Authors:  R Iwanaga; S Hori; H Suzuki; S Nakajima; T Saruta; S Kojima; K Fukuda; T Satoh; M Kusuhara; S Handa
Journal:  Life Sci       Date:  1988       Impact factor: 5.037

6.  Cardiovascular effects of atrial extracts in anesthetized rats.

Authors:  U Ackermann; T G Irizawa; S Milojevic; H Sonnenberg
Journal:  Can J Physiol Pharmacol       Date:  1984-07       Impact factor: 2.273

7.  Plasma levels and cardiovascular, endocrine, and excretory effects of atrial natriuretic peptide during different sodium intakes in man.

Authors:  P Weidmann; B Hellmueller; D E Uehlinger; R E Lang; M P Gnaedinger; L Hasler; S Shaw; C Bachmann
Journal:  J Clin Endocrinol Metab       Date:  1986-05       Impact factor: 5.958

8.  Blood pressure, renal and endocrine responses to alpha-human atrial natriuretic polypeptide in healthy volunteers.

Authors:  M Ishii; T Sugimoto; H Matsuoka; T Ishimitsu; K Atarashi; Y Hirata; T Sugimoto; K Kangawa; H Matsuo
Journal:  Jpn Heart J       Date:  1986-11

9.  Hemodynamic, renal, and hormonal responses to alpha-human atrial natriuretic peptide in patients with congestive heart failure.

Authors:  H Saito; T Ogihara; M Nakamaru; H Hara; J Higaki; H Rakugi; H Tateyama; T Minamino; K Iinuma; Y Kumahara
Journal:  Clin Pharmacol Ther       Date:  1987-08       Impact factor: 6.875

10.  Human atrial natriuretic peptide: plasma levels, hemodynamic, hormonal, and renal effects in patients with severe congestive heart failure.

Authors:  G A Riegger; E P Kromer; K Kochsiek
Journal:  J Cardiovasc Pharmacol       Date:  1986 Nov-Dec       Impact factor: 3.105
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